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Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR–RXR
Retinoic acid receptors (RARs) as a functional heterodimer with retinoid X receptors (RXRs), bind a diverse series of RA-response elements (RAREs) in regulated genes. Among them, the non-canonical DR0 elements are bound by RXR–RAR with comparable affinities to DR5 elements but DR0 elements do not ac...
Autores principales: | Osz, Judit, McEwen, Alastair G, Bourguet, Maxime, Przybilla, Frédéric, Peluso-Iltis, Carole, Poussin-Courmontagne, Pierre, Mély, Yves, Cianférani, Sarah, Jeffries, Cy M, Svergun, Dmitri I, Rochel, Natacha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515732/ https://www.ncbi.nlm.nih.gov/pubmed/32974652 http://dx.doi.org/10.1093/nar/gkaa697 |
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