Intravenous Immunoglobulin-Associated Elevation of Liver Enzymes in Neurological Autoimmune Disorder: A Case Series

Intravenous immunoglobulin (IVIG) is used in the treatment of a variety of autoimmune neurological disorders and is generally regarded as safe. We present a case series where IVIG causes transaminitis. The adverse effects are mostly due to the stabilizing agent used to prepare the IVIG (e.g., maltos...

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Autores principales: Behera, Anupama, Guru, Satyabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515744/
https://www.ncbi.nlm.nih.gov/pubmed/32983715
http://dx.doi.org/10.7759/cureus.10020
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author Behera, Anupama
Guru, Satyabrata
author_facet Behera, Anupama
Guru, Satyabrata
author_sort Behera, Anupama
collection PubMed
description Intravenous immunoglobulin (IVIG) is used in the treatment of a variety of autoimmune neurological disorders and is generally regarded as safe. We present a case series where IVIG causes transaminitis. The adverse effects are mostly due to the stabilizing agent used to prepare the IVIG (e.g., maltose in this series). While the adverse effects are usually self-limiting, physicians should be cautious in administering an IVIG preparation to these patients.
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spelling pubmed-75157442020-09-26 Intravenous Immunoglobulin-Associated Elevation of Liver Enzymes in Neurological Autoimmune Disorder: A Case Series Behera, Anupama Guru, Satyabrata Cureus Internal Medicine Intravenous immunoglobulin (IVIG) is used in the treatment of a variety of autoimmune neurological disorders and is generally regarded as safe. We present a case series where IVIG causes transaminitis. The adverse effects are mostly due to the stabilizing agent used to prepare the IVIG (e.g., maltose in this series). While the adverse effects are usually self-limiting, physicians should be cautious in administering an IVIG preparation to these patients. Cureus 2020-08-25 /pmc/articles/PMC7515744/ /pubmed/32983715 http://dx.doi.org/10.7759/cureus.10020 Text en Copyright © 2020, Behera et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Behera, Anupama
Guru, Satyabrata
Intravenous Immunoglobulin-Associated Elevation of Liver Enzymes in Neurological Autoimmune Disorder: A Case Series
title Intravenous Immunoglobulin-Associated Elevation of Liver Enzymes in Neurological Autoimmune Disorder: A Case Series
title_full Intravenous Immunoglobulin-Associated Elevation of Liver Enzymes in Neurological Autoimmune Disorder: A Case Series
title_fullStr Intravenous Immunoglobulin-Associated Elevation of Liver Enzymes in Neurological Autoimmune Disorder: A Case Series
title_full_unstemmed Intravenous Immunoglobulin-Associated Elevation of Liver Enzymes in Neurological Autoimmune Disorder: A Case Series
title_short Intravenous Immunoglobulin-Associated Elevation of Liver Enzymes in Neurological Autoimmune Disorder: A Case Series
title_sort intravenous immunoglobulin-associated elevation of liver enzymes in neurological autoimmune disorder: a case series
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515744/
https://www.ncbi.nlm.nih.gov/pubmed/32983715
http://dx.doi.org/10.7759/cureus.10020
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