Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions

From viruses to nanoparticles, constructs functionalized with multiple ligands display peculiar binding properties that only arise from multivalent effects. Using statistical mechanical modelling, we describe here how multivalency can be exploited to achieve what we dub range selectivity, that is, b...

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Detalles Bibliográficos
Autores principales: Liu, Meng, Apriceno, Azzurra, Sipin, Miguel, Scarpa, Edoardo, Rodriguez-Arco, Laura, Poma, Alessandro, Marchello, Gabriele, Battaglia, Giuseppe, Angioletti-Uberti, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515919/
https://www.ncbi.nlm.nih.gov/pubmed/32973157
http://dx.doi.org/10.1038/s41467-020-18603-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515919/
https://www.ncbi.nlm.nih.gov/pubmed/32973157
http://dx.doi.org/10.1038/s41467-020-18603-5

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