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Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions
From viruses to nanoparticles, constructs functionalized with multiple ligands display peculiar binding properties that only arise from multivalent effects. Using statistical mechanical modelling, we describe here how multivalency can be exploited to achieve what we dub range selectivity, that is, b...
Autores principales: | Liu, Meng, Apriceno, Azzurra, Sipin, Miguel, Scarpa, Edoardo, Rodriguez-Arco, Laura, Poma, Alessandro, Marchello, Gabriele, Battaglia, Giuseppe, Angioletti-Uberti, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515919/ https://www.ncbi.nlm.nih.gov/pubmed/32973157 http://dx.doi.org/10.1038/s41467-020-18603-5 |
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