MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme

ATP synthesis and thermogenesis are two critical outputs of mitochondrial respiration. How these outputs are regulated to balance the cellular requirement for energy and heat is largely unknown. Here we show that major facilitator superfamily domain containing 7C (MFSD7C) uncouples mitochondrial res...

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Detalles Bibliográficos
Autores principales: Li, Yingzhong, Ivica, Nikola A., Dong, Ting, Papageorgiou, Dimitrios P., He, Yanpu, Brown, Douglas R., Kleyman, Marianna, Hu, Guangan, Chen, Walter W., Sullivan, Lucas B., Del Rosario, Amanda, Hammond, Paula T., Vander Heiden, Matthew G., Chen, Jianzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515921/
https://www.ncbi.nlm.nih.gov/pubmed/32973183
http://dx.doi.org/10.1038/s41467-020-18607-1

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