Cargando…
Association Between Infectious Agents and Lesions in Post-Weaned Piglets and Fattening Heavy Pigs With Porcine Respiratory Disease Complex (PRDC)
Porcine Respiratory Disease Complex (PRDC) is a multifactorial syndrome that causes health problems in growing pigs and economic losses to farmers. The etiological factors involved can be bacteria, viruses, or mycoplasmas. However, environmental stressors associated with farm management can influenc...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516008/ https://www.ncbi.nlm.nih.gov/pubmed/33024748 http://dx.doi.org/10.3389/fvets.2020.00636 |
_version_ | 1783586918125010944 |
---|---|
author | Ruggeri, Jessica Salogni, Cristian Giovannini, Stefano Vitale, Nicoletta Boniotti, Maria Beatrice Corradi, Attilio Pozzi, Paolo Pasquali, Paolo Alborali, Giovanni Loris |
author_facet | Ruggeri, Jessica Salogni, Cristian Giovannini, Stefano Vitale, Nicoletta Boniotti, Maria Beatrice Corradi, Attilio Pozzi, Paolo Pasquali, Paolo Alborali, Giovanni Loris |
author_sort | Ruggeri, Jessica |
collection | PubMed |
description | Porcine Respiratory Disease Complex (PRDC) is a multifactorial syndrome that causes health problems in growing pigs and economic losses to farmers. The etiological factors involved can be bacteria, viruses, or mycoplasmas. However, environmental stressors associated with farm management can influence the status of the animal's health. The role and impact of different microorganisms in the development of the disease can be complex, and these are not fully understood. The severity of lesions are a consequence of synergism and combination of different factors. The aim of this study was to systematically analyse samples, conferred to the Veterinary Diagnostic Laboratory (IZSLER, Brescia), with a standardized diagnostic protocol in case of suspected PRDC. During necropsy, the lungs and carcasses were analyzed to determine the severity and extension of lesions. Gross lung lesions were classified according to a pre-established scheme adapted from literature. Furthermore, pulmonary, pleural, and nasal lesions were scored to determine their severity and extension. Finally, the presence of infectious agents was investigated to identify the microorganisms involved in the cases studied. During the years 2014–2016, 1,658 samples of lungs and carcasses with PRDC from 863 farms were analyzed; among them 931 and 727 samples were from weaned piglets and fattening pigs, respectively. The most frequently observed lesions were characteristic of catarrhal bronchopneumonia, broncho-interstitial pneumonia, pleuropneumonia, and pleuritis. Some pathogens identified were correlated to specific lesions, whereas other pathogens to various lesions. These underline the need for the establishment of control and treatment programmes for individual farms. |
format | Online Article Text |
id | pubmed-7516008 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-75160082020-10-05 Association Between Infectious Agents and Lesions in Post-Weaned Piglets and Fattening Heavy Pigs With Porcine Respiratory Disease Complex (PRDC) Ruggeri, Jessica Salogni, Cristian Giovannini, Stefano Vitale, Nicoletta Boniotti, Maria Beatrice Corradi, Attilio Pozzi, Paolo Pasquali, Paolo Alborali, Giovanni Loris Front Vet Sci Veterinary Science Porcine Respiratory Disease Complex (PRDC) is a multifactorial syndrome that causes health problems in growing pigs and economic losses to farmers. The etiological factors involved can be bacteria, viruses, or mycoplasmas. However, environmental stressors associated with farm management can influence the status of the animal's health. The role and impact of different microorganisms in the development of the disease can be complex, and these are not fully understood. The severity of lesions are a consequence of synergism and combination of different factors. The aim of this study was to systematically analyse samples, conferred to the Veterinary Diagnostic Laboratory (IZSLER, Brescia), with a standardized diagnostic protocol in case of suspected PRDC. During necropsy, the lungs and carcasses were analyzed to determine the severity and extension of lesions. Gross lung lesions were classified according to a pre-established scheme adapted from literature. Furthermore, pulmonary, pleural, and nasal lesions were scored to determine their severity and extension. Finally, the presence of infectious agents was investigated to identify the microorganisms involved in the cases studied. During the years 2014–2016, 1,658 samples of lungs and carcasses with PRDC from 863 farms were analyzed; among them 931 and 727 samples were from weaned piglets and fattening pigs, respectively. The most frequently observed lesions were characteristic of catarrhal bronchopneumonia, broncho-interstitial pneumonia, pleuropneumonia, and pleuritis. Some pathogens identified were correlated to specific lesions, whereas other pathogens to various lesions. These underline the need for the establishment of control and treatment programmes for individual farms. Frontiers Media S.A. 2020-09-11 /pmc/articles/PMC7516008/ /pubmed/33024748 http://dx.doi.org/10.3389/fvets.2020.00636 Text en Copyright © 2020 Ruggeri, Salogni, Giovannini, Vitale, Boniotti, Corradi, Pozzi, Pasquali and Alborali. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Veterinary Science Ruggeri, Jessica Salogni, Cristian Giovannini, Stefano Vitale, Nicoletta Boniotti, Maria Beatrice Corradi, Attilio Pozzi, Paolo Pasquali, Paolo Alborali, Giovanni Loris Association Between Infectious Agents and Lesions in Post-Weaned Piglets and Fattening Heavy Pigs With Porcine Respiratory Disease Complex (PRDC) |
title | Association Between Infectious Agents and Lesions in Post-Weaned Piglets and Fattening Heavy Pigs With Porcine Respiratory Disease Complex (PRDC) |
title_full | Association Between Infectious Agents and Lesions in Post-Weaned Piglets and Fattening Heavy Pigs With Porcine Respiratory Disease Complex (PRDC) |
title_fullStr | Association Between Infectious Agents and Lesions in Post-Weaned Piglets and Fattening Heavy Pigs With Porcine Respiratory Disease Complex (PRDC) |
title_full_unstemmed | Association Between Infectious Agents and Lesions in Post-Weaned Piglets and Fattening Heavy Pigs With Porcine Respiratory Disease Complex (PRDC) |
title_short | Association Between Infectious Agents and Lesions in Post-Weaned Piglets and Fattening Heavy Pigs With Porcine Respiratory Disease Complex (PRDC) |
title_sort | association between infectious agents and lesions in post-weaned piglets and fattening heavy pigs with porcine respiratory disease complex (prdc) |
topic | Veterinary Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516008/ https://www.ncbi.nlm.nih.gov/pubmed/33024748 http://dx.doi.org/10.3389/fvets.2020.00636 |
work_keys_str_mv | AT ruggerijessica associationbetweeninfectiousagentsandlesionsinpostweanedpigletsandfatteningheavypigswithporcinerespiratorydiseasecomplexprdc AT salognicristian associationbetweeninfectiousagentsandlesionsinpostweanedpigletsandfatteningheavypigswithporcinerespiratorydiseasecomplexprdc AT giovanninistefano associationbetweeninfectiousagentsandlesionsinpostweanedpigletsandfatteningheavypigswithporcinerespiratorydiseasecomplexprdc AT vitalenicoletta associationbetweeninfectiousagentsandlesionsinpostweanedpigletsandfatteningheavypigswithporcinerespiratorydiseasecomplexprdc AT boniottimariabeatrice associationbetweeninfectiousagentsandlesionsinpostweanedpigletsandfatteningheavypigswithporcinerespiratorydiseasecomplexprdc AT corradiattilio associationbetweeninfectiousagentsandlesionsinpostweanedpigletsandfatteningheavypigswithporcinerespiratorydiseasecomplexprdc AT pozzipaolo associationbetweeninfectiousagentsandlesionsinpostweanedpigletsandfatteningheavypigswithporcinerespiratorydiseasecomplexprdc AT pasqualipaolo associationbetweeninfectiousagentsandlesionsinpostweanedpigletsandfatteningheavypigswithporcinerespiratorydiseasecomplexprdc AT alboraligiovanniloris associationbetweeninfectiousagentsandlesionsinpostweanedpigletsandfatteningheavypigswithporcinerespiratorydiseasecomplexprdc |