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On the Progression of COVID-19 in Portugal: A Comparative Analysis of Active Cases Using Non-linear Regression

Portugal is often portrayed as a relatively successful case in the control of COVID-19's March 2020 outbreak in Europe due to timely confinement measures, commonly referred to as the “lockdown”. As in other European Union member states, by late April, Portugal was preparing the phased loosening...

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Autores principales: Milhinhos, Ana, Costa, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516009/
https://www.ncbi.nlm.nih.gov/pubmed/33014981
http://dx.doi.org/10.3389/fpubh.2020.00495
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author Milhinhos, Ana
Costa, Pedro M.
author_facet Milhinhos, Ana
Costa, Pedro M.
author_sort Milhinhos, Ana
collection PubMed
description Portugal is often portrayed as a relatively successful case in the control of COVID-19's March 2020 outbreak in Europe due to timely confinement measures, commonly referred to as the “lockdown”. As in other European Union member states, by late April, Portugal was preparing the phased loosening of such measures scheduled for the beginning of May. Despite a modest reduction in infection rates by that time, there was insufficient data to reliably forecast imminent scenarios. Using the South Korea data as scaffold, which became a paradigmatic case of recovery following a high number of infected people, we fitted the Portuguese data to biphasic models using non-linear regression and compared the two countries. The models, which yielded a good fit, showed that recovery would be slow, with over 50% active cases months after the lockdown. These findings acted at the time as a warning, showing that a high number of infected individuals, together with an unknown number of asymptomatic carriers, could increase the risk of a slow recovery, if not of new outbreaks. A month later, the models showed more favorable outcomes. However, shortly after, as the effects of leaving the lockdown became evident, the number of infections began rising again, leaving Portugal in a situation of inward and outward travel restrictions and baffling even the most conservative forecasts for the clearing of the pandemic.
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spelling pubmed-75160092020-10-02 On the Progression of COVID-19 in Portugal: A Comparative Analysis of Active Cases Using Non-linear Regression Milhinhos, Ana Costa, Pedro M. Front Public Health Public Health Portugal is often portrayed as a relatively successful case in the control of COVID-19's March 2020 outbreak in Europe due to timely confinement measures, commonly referred to as the “lockdown”. As in other European Union member states, by late April, Portugal was preparing the phased loosening of such measures scheduled for the beginning of May. Despite a modest reduction in infection rates by that time, there was insufficient data to reliably forecast imminent scenarios. Using the South Korea data as scaffold, which became a paradigmatic case of recovery following a high number of infected people, we fitted the Portuguese data to biphasic models using non-linear regression and compared the two countries. The models, which yielded a good fit, showed that recovery would be slow, with over 50% active cases months after the lockdown. These findings acted at the time as a warning, showing that a high number of infected individuals, together with an unknown number of asymptomatic carriers, could increase the risk of a slow recovery, if not of new outbreaks. A month later, the models showed more favorable outcomes. However, shortly after, as the effects of leaving the lockdown became evident, the number of infections began rising again, leaving Portugal in a situation of inward and outward travel restrictions and baffling even the most conservative forecasts for the clearing of the pandemic. Frontiers Media S.A. 2020-09-11 /pmc/articles/PMC7516009/ /pubmed/33014981 http://dx.doi.org/10.3389/fpubh.2020.00495 Text en Copyright © 2020 Milhinhos and Costa. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Milhinhos, Ana
Costa, Pedro M.
On the Progression of COVID-19 in Portugal: A Comparative Analysis of Active Cases Using Non-linear Regression
title On the Progression of COVID-19 in Portugal: A Comparative Analysis of Active Cases Using Non-linear Regression
title_full On the Progression of COVID-19 in Portugal: A Comparative Analysis of Active Cases Using Non-linear Regression
title_fullStr On the Progression of COVID-19 in Portugal: A Comparative Analysis of Active Cases Using Non-linear Regression
title_full_unstemmed On the Progression of COVID-19 in Portugal: A Comparative Analysis of Active Cases Using Non-linear Regression
title_short On the Progression of COVID-19 in Portugal: A Comparative Analysis of Active Cases Using Non-linear Regression
title_sort on the progression of covid-19 in portugal: a comparative analysis of active cases using non-linear regression
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516009/
https://www.ncbi.nlm.nih.gov/pubmed/33014981
http://dx.doi.org/10.3389/fpubh.2020.00495
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