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Organoids to Study Intestinal Nutrient Transport, Drug Uptake and Metabolism – Update to the Human Model and Expansion of Applications
Intestinal transport and sensing processes and their interconnection to metabolism are relevant to pathologies such as malabsorption syndromes, inflammatory diseases, obesity and type 2 diabetes. Constituting a highly selective barrier, intestinal epithelial cells absorb, metabolize, and release nut...
Autores principales: | Zietek, Tamara, Giesbertz, Pieter, Ewers, Maren, Reichart, Florian, Weinmüller, Michael, Urbauer, Elisabeth, Haller, Dirk, Demir, Ihsan Ekin, Ceyhan, Güralp O., Kessler, Horst, Rath, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516017/ https://www.ncbi.nlm.nih.gov/pubmed/33015026 http://dx.doi.org/10.3389/fbioe.2020.577656 |
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