CD4(+) T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice

Non-alcoholic fatty liver disease (NAFLD) has been on a global rise. While animal models have rendered valuable insights to the pathogenesis of NAFLD, discrepancy with patient data still exists. Since non-alcoholic steatohepatitis (NASH) involves chronic inflammation, and CD4(+) T cell infiltration...

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Detalles Bibliográficos
Autores principales: Her, Zhisheng, Tan, Joel Heng Loong, Lim, Yee-Siang, Tan, Sue Yee, Chan, Xue Ying, Tan, Wilson Wei Sheng, Liu, Min, Yong, Kylie Su Mei, Lai, Fritz, Ceccarello, Erica, Zheng, Zhiqiang, Fan, Yong, Chang, Kenneth Tou En, Sun, Lei, Chang, Shih Chieh, Chin, Chih-Liang, Lee, Guan Huei, Dan, Yock Young, Chan, Yun-Shen, Lim, Seng Gee, Chan, Jerry Kok Yen, Chandy, K. George, Chen, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516019/
https://www.ncbi.nlm.nih.gov/pubmed/33013934
http://dx.doi.org/10.3389/fimmu.2020.580968

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