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Shugan Decoction Alleviates Colonic Dysmotility in Female SERT-Knockout Rats by Decreasing M(3) Receptor Expression

BACKGROUND: Irritable bowel syndrome (IBS) is a functional gut disease characterized by visceral hypersensitivity and gut motor dysfunction. Serotonin (5-hydroxytryptamine, 5-HT) is an important enteric neurotransmitter. High levels of 5-HT aggravate IBS symptoms. The serotonin reuptake transporter...

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Detalles Bibliográficos
Autores principales: Wang, Yinshu, Dong, Ying, Wang, Enkang, Meng, Yangyang, Bi, Zijuan, Sun, Shuai, Zhang, Chaochao, Fan, Haiting, Yuan, Jianye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516163/
https://www.ncbi.nlm.nih.gov/pubmed/33013355
http://dx.doi.org/10.3389/fphar.2020.01082