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Inhibition of furin by bone targeting superparamagnetic iron oxide nanoparticles alleviated breast cancer bone metastasis
Breast cancer bone metastasis poses significant challenge for therapeutic strategies. Inside the metastatic environment, osteoclasts and tumor cells interact synergistically to promote cancer progression. In this study, the proprotein convertase furin is targeted due to its critical roles in both tu...
Autores principales: | Pang, Yichuan, Su, Li, Fu, Yao, Jia, Fan, Zhang, Chenxi, Cao, Xiankun, He, Wenxin, Kong, Xueqian, Xu, Jiake, Zhao, Jie, Qin, An |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516174/ https://www.ncbi.nlm.nih.gov/pubmed/33005833 http://dx.doi.org/10.1016/j.bioactmat.2020.09.006 |
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