Liraglutide activates nature killer cell-mediated antitumor responses by inhibiting IL-6/STAT3 signaling in hepatocellular carcinoma

Inflammatory IL-6/STAT3 signaling is constitutively activated in diverse cancers and is associated with malignant cell proliferation, invasion and escape of antitumor immunosurveillance. Liraglutide, a glucagon-like peptide-1 (GLP-1) analog, is commonly used to treat insulin-resistant diabetes. In t...

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Detalles Bibliográficos
Autores principales: Lu, Xian, Xu, Chun, Dong, Jie, Zuo, Shuguang, Zhang, Hailin, Jiang, Chunping, Wu, Junhua, Wei, Jiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516274/
https://www.ncbi.nlm.nih.gov/pubmed/32979685
http://dx.doi.org/10.1016/j.tranon.2020.100872

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