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Pulmonary tuberculosis presenting as lung abscess in a 10-month-Old infant

Tuberculosis in infants although less common compared to older children and adults, is associated with a high risk for milliary tuberculosis, tuberculosis meningitis and overall higher mortality. Lung abscess commonly presents following severe community acquired bacterial infections and is extremely...

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Autores principales: Thadchanamoorthy, V., Dayasiri, Kavinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516287/
https://www.ncbi.nlm.nih.gov/pubmed/32995265
http://dx.doi.org/10.1016/j.rmcr.2020.101229
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author Thadchanamoorthy, V.
Dayasiri, Kavinda
author_facet Thadchanamoorthy, V.
Dayasiri, Kavinda
author_sort Thadchanamoorthy, V.
collection PubMed
description Tuberculosis in infants although less common compared to older children and adults, is associated with a high risk for milliary tuberculosis, tuberculosis meningitis and overall higher mortality. Lung abscess commonly presents following severe community acquired bacterial infections and is extremely rare in infants with tuberculosis. This report presents the case of a 10-month-old infant who had an unusual presentation of pulmonary tuberculosis with no cough, poor growth or documented temperature >38 C despite extensive right lung involvement with lung abscess formation and pleural effusions. Inflammatory markers were minimally deranged. The diagnosis of pulmonary tuberculosis was confirmed based on positive tuberculosis polymerase chain reaction test. The child made a successful clinical and radiological recovery upon completion of anti-tuberculosis drug regimen for six months. This report brings to light that it is crucial for clinicians to have a high index of suspicion of tuberculosis irrespective of age of the patient, presenting symptoms and low prevalence since delayed diagnosis of tuberculosis in infants is associated with poor outcomes.
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spelling pubmed-75162872020-09-28 Pulmonary tuberculosis presenting as lung abscess in a 10-month-Old infant Thadchanamoorthy, V. Dayasiri, Kavinda Respir Med Case Rep Case Report Tuberculosis in infants although less common compared to older children and adults, is associated with a high risk for milliary tuberculosis, tuberculosis meningitis and overall higher mortality. Lung abscess commonly presents following severe community acquired bacterial infections and is extremely rare in infants with tuberculosis. This report presents the case of a 10-month-old infant who had an unusual presentation of pulmonary tuberculosis with no cough, poor growth or documented temperature >38 C despite extensive right lung involvement with lung abscess formation and pleural effusions. Inflammatory markers were minimally deranged. The diagnosis of pulmonary tuberculosis was confirmed based on positive tuberculosis polymerase chain reaction test. The child made a successful clinical and radiological recovery upon completion of anti-tuberculosis drug regimen for six months. This report brings to light that it is crucial for clinicians to have a high index of suspicion of tuberculosis irrespective of age of the patient, presenting symptoms and low prevalence since delayed diagnosis of tuberculosis in infants is associated with poor outcomes. Elsevier 2020-09-16 /pmc/articles/PMC7516287/ /pubmed/32995265 http://dx.doi.org/10.1016/j.rmcr.2020.101229 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Thadchanamoorthy, V.
Dayasiri, Kavinda
Pulmonary tuberculosis presenting as lung abscess in a 10-month-Old infant
title Pulmonary tuberculosis presenting as lung abscess in a 10-month-Old infant
title_full Pulmonary tuberculosis presenting as lung abscess in a 10-month-Old infant
title_fullStr Pulmonary tuberculosis presenting as lung abscess in a 10-month-Old infant
title_full_unstemmed Pulmonary tuberculosis presenting as lung abscess in a 10-month-Old infant
title_short Pulmonary tuberculosis presenting as lung abscess in a 10-month-Old infant
title_sort pulmonary tuberculosis presenting as lung abscess in a 10-month-old infant
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516287/
https://www.ncbi.nlm.nih.gov/pubmed/32995265
http://dx.doi.org/10.1016/j.rmcr.2020.101229
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