Intestinal Inflammation Modulates the Expression of ACE2 and TMPRSS2 and Potentially Overlaps With the Pathogenesis of SARS-CoV-2–related Disease

BACKGROUND AND AIMS: The presence of gastrointestinal symptoms and high levels of viral RNA in the stool suggest active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication within enterocytes. METHODS: Here, in multiple, large cohorts of patients with inflammatory bowel disease (...

Descripción completa

Detalles Bibliográficos
Autores principales: Suárez-Fariñas, Mayte, Tokuyama, Minami, Wei, Gabrielle, Huang, Ruiqi, Livanos, Alexandra, Jha, Divya, Levescot, Anais, Irizar, Haritz, Kosoy, Roman, Cording, Sascha, Wang, Wenhui, Losic, Bojan, Ungaro, Ryan C., Di’Narzo, Antonio, Martinez-Delgado, Gustavo, Suprun, Maria, Corley, Michael J., Stojmirovic, Aleksandar, Houten, Sander M., Peters, Lauren, Curran, Mark, Brodmerkel, Carrie, Perrigoue, Jacqueline, Friedman, Joshua R., Hao, Ke, Schadt, Eric E., Zhu, Jun, Ko, Huaibin M., Cho, Judy, Dubinsky, Marla C., Sands, Bruce E., Ndhlovu, Lishomwa, Cerf-Bensusan, Nadine, Kasarskis, Andrew, Colombel, Jean-Frederic, Harpaz, Noam, Argmann, Carmen, Mehandru, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: by the AGA Institute 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516468/
https://www.ncbi.nlm.nih.gov/pubmed/32980345
http://dx.doi.org/10.1053/j.gastro.2020.09.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516468/
https://www.ncbi.nlm.nih.gov/pubmed/32980345
http://dx.doi.org/10.1053/j.gastro.2020.09.029

Ejemplares similares