Variants of the human RAD52 gene confer defects in ionizing radiation resistance and homologous recombination repair in budding yeast

RAD52 is a structurally and functionally conserved component of the DNA double-strand break (DSB) repair apparatus from budding yeast to humans. We recently showed that expressing the human gene, HsRAD52 in rad52 mutant budding yeast cells can suppress both their ionizing radiation (IR) sensitivity...

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Detalles Bibliográficos
Autores principales: Clear, Alissa D., Manthey, Glenn M., Lewis, Olivia, Lopez, Isabelle Y., Rico, Rossana, Owens, Shannon, Negritto, M. Cristina, Wolf, Elise W., Xu, Jason, Kenjić, Nikola, Perry, J. Jefferson P., Adamson, Aaron W., Neuhausen, Susan L., Bailis, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517009/
https://www.ncbi.nlm.nih.gov/pubmed/33015141
http://dx.doi.org/10.15698/mic2020.10.732

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