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Identification and seasonality of rhinovirus and respiratory syncytial virus in asthmatic children in tropical climate

Introduction: Asthma is a disease that has been associated with the presence of different genetic and socio-environmental factors. Objective: To identify and evaluate the seasonality of respiratory syncytial virus (RSV) and human rhinovirus (RV) in asthmatic children and adolescents in tropical clim...

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Autores principales: Lopes, Giselmo Pinheiro, Amorim, Ítalo Patrick Souza, Melo, Bruna de Oliveira de, Maramaldo, Carlos Eduardo Campos, Bomfim, Maria Rosa Quaresma, Lima Neto, Lídio Gonçalves, Alves, Matheus Silva, Silva, Fabrício Brito, Soeiro-Pereira, Paulo Vítor, Falcai, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517263/
https://www.ncbi.nlm.nih.gov/pubmed/32914848
http://dx.doi.org/10.1042/BSR20200634
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author Lopes, Giselmo Pinheiro
Amorim, Ítalo Patrick Souza
Melo, Bruna de Oliveira de
Maramaldo, Carlos Eduardo Campos
Bomfim, Maria Rosa Quaresma
Lima Neto, Lídio Gonçalves
Alves, Matheus Silva
Silva, Fabrício Brito
Soeiro-Pereira, Paulo Vítor
Falcai, Angela
author_facet Lopes, Giselmo Pinheiro
Amorim, Ítalo Patrick Souza
Melo, Bruna de Oliveira de
Maramaldo, Carlos Eduardo Campos
Bomfim, Maria Rosa Quaresma
Lima Neto, Lídio Gonçalves
Alves, Matheus Silva
Silva, Fabrício Brito
Soeiro-Pereira, Paulo Vítor
Falcai, Angela
author_sort Lopes, Giselmo Pinheiro
collection PubMed
description Introduction: Asthma is a disease that has been associated with the presence of different genetic and socio-environmental factors. Objective: To identify and evaluate the seasonality of respiratory syncytial virus (RSV) and human rhinovirus (RV) in asthmatic children and adolescents in tropical climate, as well as to assess the socioeconomic and environmental factors involved. Methods: The study was conducted in a referral hospital, where a total of 151 children were recruited with a respiratory infection. The International Study of Asthma and Allergies in Childhood (ISAAC) protocol and a questionnaire were applied, and a skin prick test was performed. The nasal swab was collected to detect RV and RSV through molecular assay. National Meteorological Institute (INMET) database was the source of climatic information. Results: The socio-environmental characterization of asthmatic children showed the family history of allergy, disturbed sleep at night, dry cough, allergic rhinitis, individuals sensitized to at least one mite. We identified RV in 75% of children with asthma and 66.7% of RSV in children with asthma. There was an association between the presence of RV and the dry season whereas the presence of the RSV was associated with the rainy season. Contributing to these results, a negative correlation was observed between the RSV and the wind speed and the maximum temperature (T. Max) and a positive correlation with precipitation. Conclusions: The results suggest a high prevalence of RV and RSV in asthmatic children and the seasonality of these viruses were present in different climatic periods. This has significant implications for understanding short- and long-term clinical complications in asthmatic patients.
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spelling pubmed-75172632020-10-02 Identification and seasonality of rhinovirus and respiratory syncytial virus in asthmatic children in tropical climate Lopes, Giselmo Pinheiro Amorim, Ítalo Patrick Souza Melo, Bruna de Oliveira de Maramaldo, Carlos Eduardo Campos Bomfim, Maria Rosa Quaresma Lima Neto, Lídio Gonçalves Alves, Matheus Silva Silva, Fabrício Brito Soeiro-Pereira, Paulo Vítor Falcai, Angela Biosci Rep Virology Introduction: Asthma is a disease that has been associated with the presence of different genetic and socio-environmental factors. Objective: To identify and evaluate the seasonality of respiratory syncytial virus (RSV) and human rhinovirus (RV) in asthmatic children and adolescents in tropical climate, as well as to assess the socioeconomic and environmental factors involved. Methods: The study was conducted in a referral hospital, where a total of 151 children were recruited with a respiratory infection. The International Study of Asthma and Allergies in Childhood (ISAAC) protocol and a questionnaire were applied, and a skin prick test was performed. The nasal swab was collected to detect RV and RSV through molecular assay. National Meteorological Institute (INMET) database was the source of climatic information. Results: The socio-environmental characterization of asthmatic children showed the family history of allergy, disturbed sleep at night, dry cough, allergic rhinitis, individuals sensitized to at least one mite. We identified RV in 75% of children with asthma and 66.7% of RSV in children with asthma. There was an association between the presence of RV and the dry season whereas the presence of the RSV was associated with the rainy season. Contributing to these results, a negative correlation was observed between the RSV and the wind speed and the maximum temperature (T. Max) and a positive correlation with precipitation. Conclusions: The results suggest a high prevalence of RV and RSV in asthmatic children and the seasonality of these viruses were present in different climatic periods. This has significant implications for understanding short- and long-term clinical complications in asthmatic patients. Portland Press Ltd. 2020-09-24 /pmc/articles/PMC7517263/ /pubmed/32914848 http://dx.doi.org/10.1042/BSR20200634 Text en © 2020 The Author(s). https://creativecommons.org/licenses/by/4.0/ This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY).
spellingShingle Virology
Lopes, Giselmo Pinheiro
Amorim, Ítalo Patrick Souza
Melo, Bruna de Oliveira de
Maramaldo, Carlos Eduardo Campos
Bomfim, Maria Rosa Quaresma
Lima Neto, Lídio Gonçalves
Alves, Matheus Silva
Silva, Fabrício Brito
Soeiro-Pereira, Paulo Vítor
Falcai, Angela
Identification and seasonality of rhinovirus and respiratory syncytial virus in asthmatic children in tropical climate
title Identification and seasonality of rhinovirus and respiratory syncytial virus in asthmatic children in tropical climate
title_full Identification and seasonality of rhinovirus and respiratory syncytial virus in asthmatic children in tropical climate
title_fullStr Identification and seasonality of rhinovirus and respiratory syncytial virus in asthmatic children in tropical climate
title_full_unstemmed Identification and seasonality of rhinovirus and respiratory syncytial virus in asthmatic children in tropical climate
title_short Identification and seasonality of rhinovirus and respiratory syncytial virus in asthmatic children in tropical climate
title_sort identification and seasonality of rhinovirus and respiratory syncytial virus in asthmatic children in tropical climate
topic Virology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517263/
https://www.ncbi.nlm.nih.gov/pubmed/32914848
http://dx.doi.org/10.1042/BSR20200634
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