Cargando…

Thermal Resonance and Cell Behavior

From a thermodynamic point of view, living cell life is no more than a cyclic process. It starts with the newly separated daughter cells and restarts when the next generations grow as free entities. During this cycle, the cell changes its entropy. In cancer, the growth control is damaged. In this pa...

Descripción completa

Detalles Bibliográficos
Autores principales: Lucia, Umberto, Grisolia, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517324/
https://www.ncbi.nlm.nih.gov/pubmed/33286546
http://dx.doi.org/10.3390/e22070774
_version_ 1783587204117823488
author Lucia, Umberto
Grisolia, Giulia
author_facet Lucia, Umberto
Grisolia, Giulia
author_sort Lucia, Umberto
collection PubMed
description From a thermodynamic point of view, living cell life is no more than a cyclic process. It starts with the newly separated daughter cells and restarts when the next generations grow as free entities. During this cycle, the cell changes its entropy. In cancer, the growth control is damaged. In this paper, we analyze the role of the volume–area ratio in the cell in relation to the heat exchange between cell and its environment in order to point out its effect on cancer growth. The result holds to a possible control of the cancer growth based on the heat exchanged by the cancer toward its environment and the membrane potential variation, with the consequence of controlling the ions fluxes and the related biochemical reactions. This second law approach could represent a starting point for a possible future support for the anticancer therapies, in order to improve their effectiveness for the untreatable cancers.
format Online
Article
Text
id pubmed-7517324
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-75173242020-11-09 Thermal Resonance and Cell Behavior Lucia, Umberto Grisolia, Giulia Entropy (Basel) Article From a thermodynamic point of view, living cell life is no more than a cyclic process. It starts with the newly separated daughter cells and restarts when the next generations grow as free entities. During this cycle, the cell changes its entropy. In cancer, the growth control is damaged. In this paper, we analyze the role of the volume–area ratio in the cell in relation to the heat exchange between cell and its environment in order to point out its effect on cancer growth. The result holds to a possible control of the cancer growth based on the heat exchanged by the cancer toward its environment and the membrane potential variation, with the consequence of controlling the ions fluxes and the related biochemical reactions. This second law approach could represent a starting point for a possible future support for the anticancer therapies, in order to improve their effectiveness for the untreatable cancers. MDPI 2020-07-16 /pmc/articles/PMC7517324/ /pubmed/33286546 http://dx.doi.org/10.3390/e22070774 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lucia, Umberto
Grisolia, Giulia
Thermal Resonance and Cell Behavior
title Thermal Resonance and Cell Behavior
title_full Thermal Resonance and Cell Behavior
title_fullStr Thermal Resonance and Cell Behavior
title_full_unstemmed Thermal Resonance and Cell Behavior
title_short Thermal Resonance and Cell Behavior
title_sort thermal resonance and cell behavior
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517324/
https://www.ncbi.nlm.nih.gov/pubmed/33286546
http://dx.doi.org/10.3390/e22070774
work_keys_str_mv AT luciaumberto thermalresonanceandcellbehavior
AT grisoliagiulia thermalresonanceandcellbehavior