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Thermal Resonance and Cell Behavior
From a thermodynamic point of view, living cell life is no more than a cyclic process. It starts with the newly separated daughter cells and restarts when the next generations grow as free entities. During this cycle, the cell changes its entropy. In cancer, the growth control is damaged. In this pa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517324/ https://www.ncbi.nlm.nih.gov/pubmed/33286546 http://dx.doi.org/10.3390/e22070774 |
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author | Lucia, Umberto Grisolia, Giulia |
author_facet | Lucia, Umberto Grisolia, Giulia |
author_sort | Lucia, Umberto |
collection | PubMed |
description | From a thermodynamic point of view, living cell life is no more than a cyclic process. It starts with the newly separated daughter cells and restarts when the next generations grow as free entities. During this cycle, the cell changes its entropy. In cancer, the growth control is damaged. In this paper, we analyze the role of the volume–area ratio in the cell in relation to the heat exchange between cell and its environment in order to point out its effect on cancer growth. The result holds to a possible control of the cancer growth based on the heat exchanged by the cancer toward its environment and the membrane potential variation, with the consequence of controlling the ions fluxes and the related biochemical reactions. This second law approach could represent a starting point for a possible future support for the anticancer therapies, in order to improve their effectiveness for the untreatable cancers. |
format | Online Article Text |
id | pubmed-7517324 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75173242020-11-09 Thermal Resonance and Cell Behavior Lucia, Umberto Grisolia, Giulia Entropy (Basel) Article From a thermodynamic point of view, living cell life is no more than a cyclic process. It starts with the newly separated daughter cells and restarts when the next generations grow as free entities. During this cycle, the cell changes its entropy. In cancer, the growth control is damaged. In this paper, we analyze the role of the volume–area ratio in the cell in relation to the heat exchange between cell and its environment in order to point out its effect on cancer growth. The result holds to a possible control of the cancer growth based on the heat exchanged by the cancer toward its environment and the membrane potential variation, with the consequence of controlling the ions fluxes and the related biochemical reactions. This second law approach could represent a starting point for a possible future support for the anticancer therapies, in order to improve their effectiveness for the untreatable cancers. MDPI 2020-07-16 /pmc/articles/PMC7517324/ /pubmed/33286546 http://dx.doi.org/10.3390/e22070774 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lucia, Umberto Grisolia, Giulia Thermal Resonance and Cell Behavior |
title | Thermal Resonance and Cell Behavior |
title_full | Thermal Resonance and Cell Behavior |
title_fullStr | Thermal Resonance and Cell Behavior |
title_full_unstemmed | Thermal Resonance and Cell Behavior |
title_short | Thermal Resonance and Cell Behavior |
title_sort | thermal resonance and cell behavior |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517324/ https://www.ncbi.nlm.nih.gov/pubmed/33286546 http://dx.doi.org/10.3390/e22070774 |
work_keys_str_mv | AT luciaumberto thermalresonanceandcellbehavior AT grisoliagiulia thermalresonanceandcellbehavior |