Cargando…
VapC21 Toxin Contributes to Drug-Tolerance and Interacts With Non-cognate VapB32 Antitoxin in Mycobacterium tuberculosis
The prokaryotic ubiquitous Toxin-antitoxin (TA) modules encodes for a stable toxin and an unstable antitoxin. VapBC subfamily is the most abundant Type II TA system in M. tuberculosis genome. However, the exact physiological role for most of these Type II TA systems are still unknown. Here, we have...
Autores principales: | Sharma, Arun, Chattopadhyay, Gopinath, Chopra, Pankaj, Bhasin, Munmun, Thakur, Chandrani, Agarwal, Sakshi, Ahmed, Shahbaz, Chandra, Nagasuma, Varadarajan, Raghavan, Singh, Ramandeep |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517352/ https://www.ncbi.nlm.nih.gov/pubmed/33042034 http://dx.doi.org/10.3389/fmicb.2020.02037 |
Ejemplares similares
-
VapC Toxins from Mycobacterium tuberculosis Are Ribonucleases that Differentially Inhibit Growth and Are Neutralized by Cognate VapB Antitoxins
por: Ahidjo, Bintou Ahmadou, et al.
Publicado: (2011) -
The vapB–vapC Operon of Acidovorax citrulli Functions as a Bona-fide Toxin–Antitoxin Module
por: Shavit, Reut, et al.
Publicado: (2016) -
Characterization of the Deep-Sea Streptomyces sp. SCSIO 02999 Derived VapC/VapB Toxin-Antitoxin System in Escherichia coli
por: Guo, Yunxue, et al.
Publicado: (2016) -
VapC from the Leptospiral VapBC Toxin-Antitoxin Module Displays Ribonuclease Activity on the Initiator tRNA
por: Lopes, Alexandre P. Y., et al.
Publicado: (2014) -
Regulation of Enteric vapBC Transcription: Induction by VapC Toxin Dimer-Breaking
por: Winther, Kristoffer S., et al.
Publicado: (2012)