Autologous cancer cell vaccination, adoptive T‐cell transfer, and interleukin‐2 administration results in long‐term survival for companion dogs with osteosarcoma

BACKGROUND: Osteosarcoma (OSA) in dogs is an aggressive bone tumor with frequent chemotherapy failure and translational relevance for human health. HYPOTHESIS/OBJECTIVES: We hypothesized that dogs with OSA could be treated safely by ex vivo activated T‐cells that were generated by autologous cancer...

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Detalles Bibliográficos
Autores principales: Flesner, Brian K., Wood, Gary W., Gayheart‐Walsten, Pamela, Sonderegger, F. Lynn, Henry, Carolyn J., Tate, Deborah J., Bechtel, Sandra M., Donnelly, Lindsay L., Johnson, Gayle C., Kim, Dae Young, Wahaus, Tammie A., Bryan, Jeffrey N., Reyes, Noe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
SMALL ANIMAL
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517513/
https://www.ncbi.nlm.nih.gov/pubmed/32649801
http://dx.doi.org/10.1111/jvim.15852

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