Cargando…
The Spindle-Associated Microcephaly Protein, WDR62, Is Required for Neurogenesis and Development of the Hippocampus
Primary microcephaly genes (MCPH) are required for the embryonic expansion of the mammalian cerebral cortex. However, MCPH mutations may spare growth in other regions of the developing forebrain which reinforces context-dependent functions for distinct MCPH genes in neurodevelopment. Mutations in th...
Autores principales: | Shohayeb, Belal, Ho, Uda Y., Hassan, Halah, Piper, Michael, Ng, Dominic C. H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517699/ https://www.ncbi.nlm.nih.gov/pubmed/33042990 http://dx.doi.org/10.3389/fcell.2020.549353 |
Ejemplares similares
-
Pathophysiological Significance of WDR62 and JNK Signaling in Human Diseases
por: Zhi, Yiqiang, et al.
Publicado: (2021) -
Glial-Specific Functions of Microcephaly Protein WDR62 and Interaction with the Mitotic Kinase AURKA Are Essential for Drosophila Brain Growth
por: Lim, Nicholas R., et al.
Publicado: (2017) -
WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis
por: Ho, Uda Y., et al.
Publicado: (2021) -
Microcephaly-associated protein WDR62 shuttles from the Golgi apparatus to the spindle poles in human neural progenitors
por: Dell'Amico, Claudia, et al.
Publicado: (2023) -
Mutations in WDR62 gene in Pakistani families with autosomal recessive primary microcephaly
por: Kousar, Rizwana, et al.
Publicado: (2011)