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Contribution to COVID-19 spread modelling: a physical phenomenological dissipative formalism

In this study, we propose an evolution law of COVID-19 transmission. An infinite ordered lattice represents population. Epidemic evolution is represented by a wave-like free spread starting from a first case as an epicentre. Free energy of the virus on a given day is defined equal to the natural log...

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Detalles Bibliográficos
Autores principales: Limam, Oualid, Limam, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517754/
https://www.ncbi.nlm.nih.gov/pubmed/32975714
http://dx.doi.org/10.1007/s10237-020-01387-4
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author Limam, Oualid
Limam, Mohamed
author_facet Limam, Oualid
Limam, Mohamed
author_sort Limam, Oualid
collection PubMed
description In this study, we propose an evolution law of COVID-19 transmission. An infinite ordered lattice represents population. Epidemic evolution is represented by a wave-like free spread starting from a first case as an epicentre. Free energy of the virus on a given day is defined equal to the natural logarithm of active infected cases number. We postulate a form of free energy built using thermodynamics of irreversible processes in analogy to isotherm wave propagation in solids and non-local elastic damage behaviour of materials. The proposed expression of daily free energy rate leads to dissipation of propagation introducing a parameter quantifying measures taking by governments to restrict transmission. Entropy daily rate representing disorder produced in the initial system is also explicitly defined. In this context, a simple law of evolution of infected cases as function of time is given in an iterative form. The model predicts different effects on peak of infected cases I(max) and epidemic period, including effects of population size N, effects of measures taking to restrict spread, effects of population density and effect of a parameter T similar to absolute temperature in thermodynamics. Different effects are presented first. The model is then applied to epidemic spread in Tunisia and compared with data registered since the report of the first confirmed case on March 2, 2020. It is shown that the low epidemic size in Tunisia is essentially due to a low population density and relatively strict restriction measures including lockdown and quarantine.
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spelling pubmed-75177542020-09-28 Contribution to COVID-19 spread modelling: a physical phenomenological dissipative formalism Limam, Oualid Limam, Mohamed Biomech Model Mechanobiol Short Communication In this study, we propose an evolution law of COVID-19 transmission. An infinite ordered lattice represents population. Epidemic evolution is represented by a wave-like free spread starting from a first case as an epicentre. Free energy of the virus on a given day is defined equal to the natural logarithm of active infected cases number. We postulate a form of free energy built using thermodynamics of irreversible processes in analogy to isotherm wave propagation in solids and non-local elastic damage behaviour of materials. The proposed expression of daily free energy rate leads to dissipation of propagation introducing a parameter quantifying measures taking by governments to restrict transmission. Entropy daily rate representing disorder produced in the initial system is also explicitly defined. In this context, a simple law of evolution of infected cases as function of time is given in an iterative form. The model predicts different effects on peak of infected cases I(max) and epidemic period, including effects of population size N, effects of measures taking to restrict spread, effects of population density and effect of a parameter T similar to absolute temperature in thermodynamics. Different effects are presented first. The model is then applied to epidemic spread in Tunisia and compared with data registered since the report of the first confirmed case on March 2, 2020. It is shown that the low epidemic size in Tunisia is essentially due to a low population density and relatively strict restriction measures including lockdown and quarantine. Springer Berlin Heidelberg 2020-09-25 2021 /pmc/articles/PMC7517754/ /pubmed/32975714 http://dx.doi.org/10.1007/s10237-020-01387-4 Text en © Springer-Verlag GmbH Germany, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Short Communication
Limam, Oualid
Limam, Mohamed
Contribution to COVID-19 spread modelling: a physical phenomenological dissipative formalism
title Contribution to COVID-19 spread modelling: a physical phenomenological dissipative formalism
title_full Contribution to COVID-19 spread modelling: a physical phenomenological dissipative formalism
title_fullStr Contribution to COVID-19 spread modelling: a physical phenomenological dissipative formalism
title_full_unstemmed Contribution to COVID-19 spread modelling: a physical phenomenological dissipative formalism
title_short Contribution to COVID-19 spread modelling: a physical phenomenological dissipative formalism
title_sort contribution to covid-19 spread modelling: a physical phenomenological dissipative formalism
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517754/
https://www.ncbi.nlm.nih.gov/pubmed/32975714
http://dx.doi.org/10.1007/s10237-020-01387-4
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