AL Amyloidosis: Unfolding a Complex Disease

Light chain (AL) amyloidosis is a rare plasma cell dyscrasia. An estimated 12,000 people live with the disease in the United States. AL amyloidosis occurs from the misfolding of proteins that deposit in organs (heart, kidneys, digestive tract, tongue, lungs, and nervous system), leading to progressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Rebecca, Richards, Tiffany A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Harborside Press LLC 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517759/
https://www.ncbi.nlm.nih.gov/pubmed/33425465
http://dx.doi.org/10.6004/jadpro.2019.10.8.4
_version_ 1783587288229347328
author Lu, Rebecca
Richards, Tiffany A.
author_facet Lu, Rebecca
Richards, Tiffany A.
author_sort Lu, Rebecca
collection PubMed
description Light chain (AL) amyloidosis is a rare plasma cell dyscrasia. An estimated 12,000 people live with the disease in the United States. AL amyloidosis occurs from the misfolding of proteins that deposit in organs (heart, kidneys, digestive tract, tongue, lungs, and nervous system), leading to progressive organ damage and impairment of quality of life. The treatment of AL amyloidosis has improved greatly over the past several years, with new treatments currently in development. This article will focus on the pathophysiology, diagnosis, and treatment of AL amyloidosis.
format Online
Article
Text
id pubmed-7517759
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Harborside Press LLC
record_format MEDLINE/PubMed
spelling pubmed-75177592021-01-07 AL Amyloidosis: Unfolding a Complex Disease Lu, Rebecca Richards, Tiffany A. J Adv Pract Oncol Review Light chain (AL) amyloidosis is a rare plasma cell dyscrasia. An estimated 12,000 people live with the disease in the United States. AL amyloidosis occurs from the misfolding of proteins that deposit in organs (heart, kidneys, digestive tract, tongue, lungs, and nervous system), leading to progressive organ damage and impairment of quality of life. The treatment of AL amyloidosis has improved greatly over the past several years, with new treatments currently in development. This article will focus on the pathophysiology, diagnosis, and treatment of AL amyloidosis. Harborside Press LLC 2019 2019-11-01 /pmc/articles/PMC7517759/ /pubmed/33425465 http://dx.doi.org/10.6004/jadpro.2019.10.8.4 Text en © 2019 Harborside™ http://creativecommons.org/licenses/by-nc-nd/3.0/ This article is distributed under the terms of the Creative Commons Attribution Non-Commercial Non-Derivative License, which permits unrestricted non-commercial and non-derivative use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Lu, Rebecca
Richards, Tiffany A.
AL Amyloidosis: Unfolding a Complex Disease
title AL Amyloidosis: Unfolding a Complex Disease
title_full AL Amyloidosis: Unfolding a Complex Disease
title_fullStr AL Amyloidosis: Unfolding a Complex Disease
title_full_unstemmed AL Amyloidosis: Unfolding a Complex Disease
title_short AL Amyloidosis: Unfolding a Complex Disease
title_sort al amyloidosis: unfolding a complex disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517759/
https://www.ncbi.nlm.nih.gov/pubmed/33425465
http://dx.doi.org/10.6004/jadpro.2019.10.8.4
work_keys_str_mv AT lurebecca alamyloidosisunfoldingacomplexdisease
AT richardstiffanya alamyloidosisunfoldingacomplexdisease

Ejemplares similares