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Dihydropyrimidine Dehydrogenase Deficiency: To Screen or Not to Screen?
5-fluorouracil (5-FU) and its prodrug capecitabine are frequently prescribed in oncology. While usually well tolerated, toxicity can be severe, and even life-threatening. A dihydropyrimidine dehydrogenase (DPD) deficiency can cause severe toxicity. Current testing for DPD deficiency does not meet th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Harborside Press LLC
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517765/ https://www.ncbi.nlm.nih.gov/pubmed/33542850 http://dx.doi.org/10.6004/jadpro.2020.11.1.4 |