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microRNA-216b enhances cisplatin-induced apoptosis in osteosarcoma MG63 and SaOS-2 cells by binding to JMJD2C and regulating the HIF1α/HES1 signaling axis

BACKGROUND: Although cisplatin-based chemotherapy represents the standard regimen for osteosarcoma (OS), OS patients often exhibit treatment failure and poor prognosis due to chemoresistance to cisplatin. Emerging research has highlighted the tumor suppressive properties of microRNAs (miRNAs or miRs...

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Detalles Bibliográficos
Autores principales:	Yang, Dong, Xu, Tianyang, Fan, Lin, Liu, Kaiyuan, Li, Guodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517798/ https://www.ncbi.nlm.nih.gov/pubmed/32972441 http://dx.doi.org/10.1186/s13046-020-01670-3

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