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Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management

BACKGROUND: Vestibular disease (VD), central or peripheral, can be a dramatic primary‐care presentation. Current literature describes mostly dogs examined in referral centers. HYPOTHESIS/OBJECTIVES: Describe the prevalence, presentation, clinical management, and outcomes of VD in dogs under primary...

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Autores principales: Radulescu, Sinziana Maria, Humm, Karen, Eramanis, Louis Mark, Volk, Holger A., Church, David B., Brodbelt, David, O'Neill, Dan Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517853/
https://www.ncbi.nlm.nih.gov/pubmed/32776616
http://dx.doi.org/10.1111/jvim.15869
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author Radulescu, Sinziana Maria
Humm, Karen
Eramanis, Louis Mark
Volk, Holger A.
Church, David B.
Brodbelt, David
O'Neill, Dan Gerard
author_facet Radulescu, Sinziana Maria
Humm, Karen
Eramanis, Louis Mark
Volk, Holger A.
Church, David B.
Brodbelt, David
O'Neill, Dan Gerard
author_sort Radulescu, Sinziana Maria
collection PubMed
description BACKGROUND: Vestibular disease (VD), central or peripheral, can be a dramatic primary‐care presentation. Current literature describes mostly dogs examined in referral centers. HYPOTHESIS/OBJECTIVES: Describe the prevalence, presentation, clinical management, and outcomes of VD in dogs under primary veterinary care at UK practices participating in VetCompass. ANIMALS: Seven hundred and fifty‐nine vestibular cases identified out of 905 544 study dogs. METHODS: Retrospective cohort study. Potential VD cases clinically examined during 2016 were verified by reviewing clinical records for signalment, presenting clinical signs, treatments, and outcomes. Multivariable logistic regression was used to evaluate factors associated with VD. RESULTS: The overall prevalence of VD was 8 per 10 000 dogs (95% CI = 7‐9). Median age at first diagnosis was 12.68 years (interquartile range [IQR], 11.28‐14.64). Compared with crossbreeds, breeds with the highest odds of VD diagnosis included French Bulldogs (odds ratio [OR] = 9.25, 95% CI = 4.81‐17.76, P < .001), Bulldogs (OR = 6.53, 95% CI = 2.66‐16.15, P < .001), King Charles Spaniels (OR = 4.96, 95% CI = 2.52‐9.78, P < .001), Cavalier King Charles Spaniels (OR = 3.56, 95% CI = 2.50‐5.06, P < .001), and Springer Spaniels (OR = 3.37, 95% CI = 2.52‐4.52, P < .001). The most common presenting signs were head tilt (69.8%), nystagmus (68.1%), and ataxia (64.5%). The most frequently used treatments were antiemetics (43.2%), systemic glucocorticoids (33.1%), antimicrobials (25%), and propentofylline (23.25%). There were 3.6% of cases referred. Improvement was recorded in 41.8% cases after a median of 4 days (IQR, 2‐10.25). CONCLUSIONS: Our study identifies strong breed predispositions for VD. The low referral rates suggest that primary‐care data sources offer more generalizable information for benchmarking to help clinicians review their own clinical activities.
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spelling pubmed-75178532020-09-30 Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management Radulescu, Sinziana Maria Humm, Karen Eramanis, Louis Mark Volk, Holger A. Church, David B. Brodbelt, David O'Neill, Dan Gerard J Vet Intern Med SMALL ANIMAL BACKGROUND: Vestibular disease (VD), central or peripheral, can be a dramatic primary‐care presentation. Current literature describes mostly dogs examined in referral centers. HYPOTHESIS/OBJECTIVES: Describe the prevalence, presentation, clinical management, and outcomes of VD in dogs under primary veterinary care at UK practices participating in VetCompass. ANIMALS: Seven hundred and fifty‐nine vestibular cases identified out of 905 544 study dogs. METHODS: Retrospective cohort study. Potential VD cases clinically examined during 2016 were verified by reviewing clinical records for signalment, presenting clinical signs, treatments, and outcomes. Multivariable logistic regression was used to evaluate factors associated with VD. RESULTS: The overall prevalence of VD was 8 per 10 000 dogs (95% CI = 7‐9). Median age at first diagnosis was 12.68 years (interquartile range [IQR], 11.28‐14.64). Compared with crossbreeds, breeds with the highest odds of VD diagnosis included French Bulldogs (odds ratio [OR] = 9.25, 95% CI = 4.81‐17.76, P < .001), Bulldogs (OR = 6.53, 95% CI = 2.66‐16.15, P < .001), King Charles Spaniels (OR = 4.96, 95% CI = 2.52‐9.78, P < .001), Cavalier King Charles Spaniels (OR = 3.56, 95% CI = 2.50‐5.06, P < .001), and Springer Spaniels (OR = 3.37, 95% CI = 2.52‐4.52, P < .001). The most common presenting signs were head tilt (69.8%), nystagmus (68.1%), and ataxia (64.5%). The most frequently used treatments were antiemetics (43.2%), systemic glucocorticoids (33.1%), antimicrobials (25%), and propentofylline (23.25%). There were 3.6% of cases referred. Improvement was recorded in 41.8% cases after a median of 4 days (IQR, 2‐10.25). CONCLUSIONS: Our study identifies strong breed predispositions for VD. The low referral rates suggest that primary‐care data sources offer more generalizable information for benchmarking to help clinicians review their own clinical activities. John Wiley & Sons, Inc. 2020-08-10 2020-09 /pmc/articles/PMC7517853/ /pubmed/32776616 http://dx.doi.org/10.1111/jvim.15869 Text en © 2020 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle SMALL ANIMAL
Radulescu, Sinziana Maria
Humm, Karen
Eramanis, Louis Mark
Volk, Holger A.
Church, David B.
Brodbelt, David
O'Neill, Dan Gerard
Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management
title Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management
title_full Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management
title_fullStr Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management
title_full_unstemmed Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management
title_short Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management
title_sort vestibular disease in dogs under uk primary veterinary care: epidemiology and clinical management
topic SMALL ANIMAL
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517853/
https://www.ncbi.nlm.nih.gov/pubmed/32776616
http://dx.doi.org/10.1111/jvim.15869
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