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Prevalence of seizures in dogs and cats with idiopathic internal hydrocephalus and seizure prevalence after implantation of a ventriculo‐peritoneal shunt

BACKGROUND: Seizures are considered a clinical sign in dogs with internal hydrocephalus but are not found in recent studies. Seizure prevalence due to ventricular enlargement and the prevalence of postoperative seizures in animals is not known. OBJECTIVES: To determine seizure prevalence in dogs and...

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Autores principales: Farke, Daniela, Kolecka, Malgorzata, Czerwik, Adriana, Wrzosek, Marcin, Schaub, Sebastian, Kramer, Martin, Failing, Klaus, Schmidt, Martin Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517859/
https://www.ncbi.nlm.nih.gov/pubmed/32918850
http://dx.doi.org/10.1111/jvim.15890
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author Farke, Daniela
Kolecka, Malgorzata
Czerwik, Adriana
Wrzosek, Marcin
Schaub, Sebastian
Kramer, Martin
Failing, Klaus
Schmidt, Martin Jürgen
author_facet Farke, Daniela
Kolecka, Malgorzata
Czerwik, Adriana
Wrzosek, Marcin
Schaub, Sebastian
Kramer, Martin
Failing, Klaus
Schmidt, Martin Jürgen
author_sort Farke, Daniela
collection PubMed
description BACKGROUND: Seizures are considered a clinical sign in dogs with internal hydrocephalus but are not found in recent studies. Seizure prevalence due to ventricular enlargement and the prevalence of postoperative seizures in animals is not known. OBJECTIVES: To determine seizure prevalence in dogs and cats with idiopathic internal hydrocephalus, to identify risk factors for seizure development, and to determine seizure prevalence in a 2‐year period after ventriculo‐peritoneal shunting (VPS). ANIMALS: Records and MRIs of 197 animals from 2001 to December 2019 were investigated. A total of 121 animals (98 dogs and 23 cats) were included in the study. METHODS: A retrospective multicenter case cohort study was conducted. Databases were searched for dogs and cats with internal hydrocephalus. MRI and CSF examinations were evaluated for signs of additional underlying disorders. Prevalence of seizures was estimated for animals showing only hydrocephalus internus. Risk factors were evaluated according to age, morphometric and morphological findings in the brain. All animals that underwent surgery were reexamined 2 years after surgery. RESULTS: One hundred twenty‐one animals (98 dogs and 23 cats) with internal hydrocephalus met the inclusion criteria. Seizure prevalence in dogs and cats with internal hydrocephalus was low (1.7%; <5.8% CI 95%). Seizures were not observed in the 2‐year period after surgery. CONCLUSION AND CLINICAL IMPORTANCE: Seizure prevalence in dogs and cats diagnosed with hydrocephalus internus is low. Seizures in association with VPS do not seem to be a complication of the procedure.
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spelling pubmed-75178592020-09-30 Prevalence of seizures in dogs and cats with idiopathic internal hydrocephalus and seizure prevalence after implantation of a ventriculo‐peritoneal shunt Farke, Daniela Kolecka, Malgorzata Czerwik, Adriana Wrzosek, Marcin Schaub, Sebastian Kramer, Martin Failing, Klaus Schmidt, Martin Jürgen J Vet Intern Med SMALL ANIMAL BACKGROUND: Seizures are considered a clinical sign in dogs with internal hydrocephalus but are not found in recent studies. Seizure prevalence due to ventricular enlargement and the prevalence of postoperative seizures in animals is not known. OBJECTIVES: To determine seizure prevalence in dogs and cats with idiopathic internal hydrocephalus, to identify risk factors for seizure development, and to determine seizure prevalence in a 2‐year period after ventriculo‐peritoneal shunting (VPS). ANIMALS: Records and MRIs of 197 animals from 2001 to December 2019 were investigated. A total of 121 animals (98 dogs and 23 cats) were included in the study. METHODS: A retrospective multicenter case cohort study was conducted. Databases were searched for dogs and cats with internal hydrocephalus. MRI and CSF examinations were evaluated for signs of additional underlying disorders. Prevalence of seizures was estimated for animals showing only hydrocephalus internus. Risk factors were evaluated according to age, morphometric and morphological findings in the brain. All animals that underwent surgery were reexamined 2 years after surgery. RESULTS: One hundred twenty‐one animals (98 dogs and 23 cats) with internal hydrocephalus met the inclusion criteria. Seizure prevalence in dogs and cats with internal hydrocephalus was low (1.7%; <5.8% CI 95%). Seizures were not observed in the 2‐year period after surgery. CONCLUSION AND CLINICAL IMPORTANCE: Seizure prevalence in dogs and cats diagnosed with hydrocephalus internus is low. Seizures in association with VPS do not seem to be a complication of the procedure. John Wiley & Sons, Inc. 2020-09-12 2020-09 /pmc/articles/PMC7517859/ /pubmed/32918850 http://dx.doi.org/10.1111/jvim.15890 Text en © 2020 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC. on behalf of the American College of Veterinary Internal Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle SMALL ANIMAL
Farke, Daniela
Kolecka, Malgorzata
Czerwik, Adriana
Wrzosek, Marcin
Schaub, Sebastian
Kramer, Martin
Failing, Klaus
Schmidt, Martin Jürgen
Prevalence of seizures in dogs and cats with idiopathic internal hydrocephalus and seizure prevalence after implantation of a ventriculo‐peritoneal shunt
title Prevalence of seizures in dogs and cats with idiopathic internal hydrocephalus and seizure prevalence after implantation of a ventriculo‐peritoneal shunt
title_full Prevalence of seizures in dogs and cats with idiopathic internal hydrocephalus and seizure prevalence after implantation of a ventriculo‐peritoneal shunt
title_fullStr Prevalence of seizures in dogs and cats with idiopathic internal hydrocephalus and seizure prevalence after implantation of a ventriculo‐peritoneal shunt
title_full_unstemmed Prevalence of seizures in dogs and cats with idiopathic internal hydrocephalus and seizure prevalence after implantation of a ventriculo‐peritoneal shunt
title_short Prevalence of seizures in dogs and cats with idiopathic internal hydrocephalus and seizure prevalence after implantation of a ventriculo‐peritoneal shunt
title_sort prevalence of seizures in dogs and cats with idiopathic internal hydrocephalus and seizure prevalence after implantation of a ventriculo‐peritoneal shunt
topic SMALL ANIMAL
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517859/
https://www.ncbi.nlm.nih.gov/pubmed/32918850
http://dx.doi.org/10.1111/jvim.15890
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