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AR420626, a selective agonist of GPR41/FFA3, suppresses growth of hepatocellular carcinoma cells by inducing apoptosis via HDAC inhibition

BACKGROUND: Hepatocellular carcinoma (HCC) is a major cause of cancer death worldwide and establishment of new chemotherapies for HCC is urgently needed. GPR41 [free fatty acid receptor 3 (FFA3)] is a G protein-coupled receptor for short chain fatty acids, including acetate, propionate, and butyrate...

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Detalles Bibliográficos
Autores principales:	Mikami, Daisuke, Kobayashi, Mamiko, Uwada, Junsuke, Yazawa, Takashi, Kamiyama, Kazuko, Nishimori, Kazuhisa, Nishikawa, Yudai, Nishikawa, Sho, Yokoi, Seiji, Taniguchi, Takanobu, Iwano, Masayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517987/ https://www.ncbi.nlm.nih.gov/pubmed/33014144 http://dx.doi.org/10.1177/1758835920913432

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