Inhibition of Angiotensin Converting Enzyme Impairs Anti-staphylococcal Immune Function in a Preclinical Model of Implant Infection

Background: Evidence suggests the renin-angiotensin system (RAS) plays key immunomodulatory roles. In particular, angiotensin-converting enzyme (ACE) has been shown to play a role in antimicrobial host defense. ACE inhibitors (ACEi) and angiotensin receptor blockers (ARB) are some of the most common...

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Detalles Bibliográficos
Autores principales: Trikha, Rishi, Greig, Danielle, Kelley, Benjamin V., Mamouei, Zeinab, Sekimura, Troy, Cevallos, Nicolas, Olson, Thomas, Chaudry, Ameen, Magyar, Clara, Leisman, Daniel, Stavrakis, Alexandra, Yeaman, Michael R., Bernthal, Nicholas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518049/
https://www.ncbi.nlm.nih.gov/pubmed/33042111
http://dx.doi.org/10.3389/fimmu.2020.01919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518049/
https://www.ncbi.nlm.nih.gov/pubmed/33042111
http://dx.doi.org/10.3389/fimmu.2020.01919

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