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Inhibition of Angiotensin Converting Enzyme Impairs Anti-staphylococcal Immune Function in a Preclinical Model of Implant Infection
Background: Evidence suggests the renin-angiotensin system (RAS) plays key immunomodulatory roles. In particular, angiotensin-converting enzyme (ACE) has been shown to play a role in antimicrobial host defense. ACE inhibitors (ACEi) and angiotensin receptor blockers (ARB) are some of the most common...
Autores principales: | Trikha, Rishi, Greig, Danielle, Kelley, Benjamin V., Mamouei, Zeinab, Sekimura, Troy, Cevallos, Nicolas, Olson, Thomas, Chaudry, Ameen, Magyar, Clara, Leisman, Daniel, Stavrakis, Alexandra, Yeaman, Michael R., Bernthal, Nicholas M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518049/ https://www.ncbi.nlm.nih.gov/pubmed/33042111 http://dx.doi.org/10.3389/fimmu.2020.01919 |
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