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Intravitreal injection of peptides PnPa11 and PnPa13, derivatives of Phoneutria nigriventer spider venom, prevents retinal damage

BACKGROUND: PnPa11 and PnPa13 are synthetic peptides derived from Phoneutria nigriventer spider venom, which display antinociceptive and neuroprotective properties. In this work, we evaluated the safety of intravitreal use and the neuroprotective effect of these peptides. METHODS: The cytotoxicity a...

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Detalles Bibliográficos
Autores principales: Dourado, Lays Fernanda Nunes, da Silva, Flavia Rodrigues, Toledo, Cibele Rodrigues, da Silva, Carolina Nunes, Santana, Cleildo Pereira, da Costa, Bruna Lopes, de Lima, Maria Elena, Cunha, Armando da Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518191/
https://www.ncbi.nlm.nih.gov/pubmed/33014024
http://dx.doi.org/10.1590/1678-9199-JVATITD-2020-0031