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Intravitreal injection of peptides PnPa11 and PnPa13, derivatives of Phoneutria nigriventer spider venom, prevents retinal damage
BACKGROUND: PnPa11 and PnPa13 are synthetic peptides derived from Phoneutria nigriventer spider venom, which display antinociceptive and neuroprotective properties. In this work, we evaluated the safety of intravitreal use and the neuroprotective effect of these peptides. METHODS: The cytotoxicity a...
Autores principales: | Dourado, Lays Fernanda Nunes, da Silva, Flavia Rodrigues, Toledo, Cibele Rodrigues, da Silva, Carolina Nunes, Santana, Cleildo Pereira, da Costa, Bruna Lopes, de Lima, Maria Elena, Cunha, Armando da Silva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centro de Estudos de Venenos e Animais Peçonhentos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518191/ https://www.ncbi.nlm.nih.gov/pubmed/33014024 http://dx.doi.org/10.1590/1678-9199-JVATITD-2020-0031 |
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