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Nanoparticle enhanced combination therapy for stem-like progenitors defined by single-cell transcriptomics in chemotherapy-resistant osteosarcoma
The adaptation of osteosarcoma cells to therapeutic pressure impedes the efficacy of chemotherapy for osteosarcoma. However, the characteristics and cellular organization of therapy-resistant cells in osteosarcoma tumors remain elusive. Here, we utilized single-cell transcriptomics to systematically...
Autores principales: | Wang, Li, Huang, Xiaojia, You, Xinru, Yi, Tianqi, Lu, Bing, Liu, Jiali, Lu, Guohao, Ma, Minglin, Zou, Changye, Wu, Jun, Zhao, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518281/ https://www.ncbi.nlm.nih.gov/pubmed/32973147 http://dx.doi.org/10.1038/s41392-020-00248-x |
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