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Nanoparticle enhanced combination therapy for stem-like progenitors defined by single-cell transcriptomics in chemotherapy-resistant osteosarcoma

The adaptation of osteosarcoma cells to therapeutic pressure impedes the efficacy of chemotherapy for osteosarcoma. However, the characteristics and cellular organization of therapy-resistant cells in osteosarcoma tumors remain elusive. Here, we utilized single-cell transcriptomics to systematically...

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Detalles Bibliográficos
Autores principales: Wang, Li, Huang, Xiaojia, You, Xinru, Yi, Tianqi, Lu, Bing, Liu, Jiali, Lu, Guohao, Ma, Minglin, Zou, Changye, Wu, Jun, Zhao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518281/
https://www.ncbi.nlm.nih.gov/pubmed/32973147
http://dx.doi.org/10.1038/s41392-020-00248-x

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