Cargando…

Enhanced Contextual Fear Memory and Elevated Astroglial Glutamate Synthase Activity in Hippocampal CA1 BChE shRNA Knockdown Mice

Butyrylcholinesterase (BChE) efficiently hydrolyzes acetylcholine (ACh) at high concentrations when acetylcholinesterase (AChE) is substrate-inhibited. Recent studies have shown that BChE also has a function that is independent of ACh, but it has not been fully explored. Low BChE expression is accom...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Si, Lin, Zhengdong, Tan, Kai-Leng, Chen, Risheng, Su, Wenfang, Zhao, Haishan, Tan, Qiwen, Tan, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518375/
https://www.ncbi.nlm.nih.gov/pubmed/33061920
http://dx.doi.org/10.3389/fpsyt.2020.564843