Cargando…

Enhanced Contextual Fear Memory and Elevated Astroglial Glutamate Synthase Activity in Hippocampal CA1 BChE shRNA Knockdown Mice

Butyrylcholinesterase (BChE) efficiently hydrolyzes acetylcholine (ACh) at high concentrations when acetylcholinesterase (AChE) is substrate-inhibited. Recent studies have shown that BChE also has a function that is independent of ACh, but it has not been fully explored. Low BChE expression is accom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Si, Lin, Zhengdong, Tan, Kai-Leng, Chen, Risheng, Su, Wenfang, Zhao, Haishan, Tan, Qiwen, Tan, Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518375/ https://www.ncbi.nlm.nih.gov/pubmed/33061920 http://dx.doi.org/10.3389/fpsyt.2020.564843

Ejemplares similares

Novel Sulfonamide-Based Carbamates as Selective Inhibitors of BChE
por: Magar, Pratibha, et al.
Publicado: (2021)

Biphasic Alteration of Butyrylcholinesterase (BChE) During Prostate Cancer Development
por: Gu, Yan, et al.
Publicado: (2018)

Characterization of the Transient Oxaphosphetane BChE Inhibitor Formed from Spontaneously Activated Ethephon
por: Lantz, Stephen R., et al.
Publicado: (2013)

Gestational diabetes mellitus (GDM) decreases butyrylcholinesterase (BChE) activity and changes its relationship with lipids
por: Guimarães, Larissa O., et al.
Publicado: (2014)

Discovery of Selective Butyrylcholinesterase (BChE) Inhibitors through a Combination of Computational Studies and Biological Evaluations
por: Zhou, You, et al.
Publicado: (2019)

Preoperative BChE serves as a prognostic marker in patients with resectable AEG after neoadjuvant chemotherapy
por: Gensthaler, Lisa, et al.
Publicado: (2023)

SAR-mediated Similarity Assessment of the Property Profile for New, Silicon-Based AChE/BChE Inhibitors
por: Bak, Andrzej, et al.
Publicado: (2019)

Extending the lore of curcumin as dipteran Butyrylcholine esterase (BChE) inhibitor: A holistic molecular interplay assessment
por: Rao, Priyashi, et al.
Publicado: (2022)

Biochemical and genetic analysis of butyrylcholinesterase (BChE) in a family, due to prolonged neuromuscular blockade after the use of succinylcholine
por: Garcia, Daniel Fantozzi, et al.
Publicado: (2011)

Novel Benzene-Based Carbamates for AChE/BChE Inhibition: Synthesis and Ligand/Structure-Oriented SAR Study
por: Bak, Andrzej, et al.
Publicado: (2019)

Differences in plasmatic butyrylcholinesterases (BChE) values between Pacific and Caribbean populations of terciopelo (Bothrops asper) in Costa Rica
por: Arguedas, Randall, et al.
Publicado: (2019)

Suppression of Cancer Progression by MGAT1 shRNA Knockdown
por: Beheshti Zavareh, Reza, et al.
Publicado: (2012)

Criteria for effective design, construction, and gene knockdown by shRNA vectors
por: Taxman, Debra J, et al.
Publicado: (2006)

Single copy shRNA configuration for ubiquitous gene knockdown in mice
por: Seibler, Jost, et al.
Publicado: (2005)

Longitudinal evaluation of a novel BChE PET tracer as an early in vivo biomarker in the brain of a mouse model for Alzheimer disease
por: Rejc, Luka, et al.
Publicado: (2021)

In Vitro and In Silico Investigation of Polyacetylenes from Launaea capitata (Spreng.) Dandy as Potential COX-2, 5-LOX, and BchE Inhibitors
por: Abdel Bar, Fatma M., et al.
Publicado: (2023)

shRNA‑mediated knockdown of KNTC1 inhibits non-small-cell lung cancer through regulating PSMB8
por: Liu, Ruijun, et al.
Publicado: (2022)

Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-Aβ Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation
por: Jiang, Cheng-Shi, et al.
Publicado: (2019)

Reversible gene knockdown in mice using a tight, inducible shRNA expression system
por: Seibler, Jost, et al.
Publicado: (2007)

Inducible Transgenic Rat Model for Diabetes Mellitus Based on shRNA-Mediated Gene Knockdown
por: Kotnik, Katarina, et al.
Publicado: (2009)

Lentiviral vector‐encoded microRNA‐based shRNA‐mediated gene knockdown of N‐methyl‐D‐aspartate receptors in skin reduces pain
por: Liu, Chien‐Cheng, et al.
Publicado: (2016)

Adapted Resistance to the Knockdown Effect of shRNA-Derived Srsf3 siRNAs in Mouse Littermates
por: Ajiro, Masahiko, et al.
Publicado: (2015)

Construction of shRNA lentiviral vector
por: Song, Hong, et al.
Publicado: (2010)

In silico modeling of the specific inhibitory potential of thiophene-2,3-dihydro-1,5-benzothiazepine against BChE in the formation of β-amyloid plaques associated with Alzheimer's disease
por: Ul-Haq, Zaheer, et al.
Publicado: (2010)

Acorenone B: AChE and BChE Inhibitor as a Major Compound of the Essential Oil Distilled from the Ecuadorian Species Niphogeton dissecta (Benth.) J.F. Macbr
por: Calva, James, et al.
Publicado: (2017)

Optimized PCR Conditions and Increased shRNA Fold Representation Improve Reproducibility of Pooled shRNA Screens
por: Strezoska, Žaklina, et al.
Publicado: (2012)

Astroglial Glutamate Signaling and Uptake in the Hippocampus
por: Rose, Christine R., et al.
Publicado: (2018)

Design, synthesis, crystal structure, in vitro cytotoxicity evaluation, density functional theory calculations and docking studies of 2-(benzamido) benzohydrazide derivatives as potent AChE and BChE inhibitors
por: Kausar, Naghmana, et al.
Publicado: (2021)

A simple approach for multi-targeted shRNA-mediated inducible knockdowns using Sleeping Beauty vectors
por: Fink, Severin, et al.
Publicado: (2018)

Knockdown of NF-κB1 by shRNA Inhibits the Growth of Renal Cell Carcinoma In Vitro and In Vivo
por: Ikegami, Amanda, et al.
Publicado: (2018)

Rapid recycling of glutamate transporters on the astroglial surface
por: Michaluk, Piotr, et al.
Publicado: (2021)

shRNA target prediction informed by comprehensive enquiry (SPICE): a supporting system for high-throughput screening of shRNA library
por: Kamatuka, Kenta, et al.
Publicado: (2016)

Systemic Delivery of shRNA by AAV9 Provides Highly Efficient Knockdown of Ubiquitously Expressed GFP in Mouse Heart, but Not Liver
por: Piras, Bryan A., et al.
Publicado: (2013)

Virus-Mediated shRNA Knockdown of Prodynorphin in the Rat Nucleus Accumbens Attenuates Depression-Like Behavior and Cocaine Locomotor Sensitization
por: Cohen, Ami, et al.
Publicado: (2014)

shRNA mediated knockdown of Nav1.7 in rat dorsal root ganglion attenuates pain following burn injury
por: Cai, Weihua, et al.
Publicado: (2016)

KRAS mutant allele-specific expression knockdown in pancreatic cancer model with systemically delivered bi-shRNA KRAS lipoplex
por: Rao, Donald D., et al.
Publicado: (2018)

Activity-Dependent Plasticity of Astroglial Potassium and Glutamate Clearance
por: Cheung, Giselle, et al.
Publicado: (2015)

Fingolimod effects in neuroinflammation: Regulation of astroglial glutamate transporters?
por: Lee, De-Hyung, et al.
Publicado: (2017)

Overexpression of a carrot BCH gene, DcBCH1, improves tolerance to drought in Arabidopsis thaliana
por: Li, Tong, et al.
Publicado: (2021)

Analysis of Blind Reconstruction of BCH Codes
por: Kwon, Soonhee, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fk88tdfdqr21mrk7gh45e9704m