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Adipocytic Progenitor Cells Give Rise to Pathogenic Myofibroblasts: Adipocyte-to-Mesenchymal Transition and Its Emerging Role in Fibrosis in Multiple Organs

PURPOSE OF REVIEW: Adipocytes have recently been shown to be able to reprogram to a myofibroblastic phenotype in a process termed adipocyte mesenchymal transition (AMT). This review seeks to discuss the relevance of this process to disease and explore its mechanisms. RECENT FINDINGS: AMT occurs in m...

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Detalles Bibliográficos
Autores principales: Marangoni, Roberta Goncalves, Korman, Benjamin, Varga, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518402/
https://www.ncbi.nlm.nih.gov/pubmed/32978695
http://dx.doi.org/10.1007/s11926-020-00957-w