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Automated rotator cuff tear classification using 3D convolutional neural network

Rotator cuff tear (RCT) is one of the most common shoulder injuries. When diagnosing RCT, skilled orthopedists visually interpret magnetic resonance imaging (MRI) scan data. For automated and accurate diagnosis of RCT, we propose a full 3D convolutional neural network (CNN) based method using deep l...

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Autores principales: Shim, Eungjune, Kim, Joon Yub, Yoon, Jong Pil, Ki, Se-Young, Lho, Taewoo, Kim, Youngjun, Chung, Seok Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518447/
https://www.ncbi.nlm.nih.gov/pubmed/32973192
http://dx.doi.org/10.1038/s41598-020-72357-0
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author Shim, Eungjune
Kim, Joon Yub
Yoon, Jong Pil
Ki, Se-Young
Lho, Taewoo
Kim, Youngjun
Chung, Seok Won
author_facet Shim, Eungjune
Kim, Joon Yub
Yoon, Jong Pil
Ki, Se-Young
Lho, Taewoo
Kim, Youngjun
Chung, Seok Won
author_sort Shim, Eungjune
collection PubMed
description Rotator cuff tear (RCT) is one of the most common shoulder injuries. When diagnosing RCT, skilled orthopedists visually interpret magnetic resonance imaging (MRI) scan data. For automated and accurate diagnosis of RCT, we propose a full 3D convolutional neural network (CNN) based method using deep learning. This 3D CNN automatically diagnoses the presence or absence of an RCT, classifies the tear size, and provides 3D visualization of the tear location. To train the 3D CNN, the Voxception-ResNet (VRN) structure was used. This architecture uses 3D convolution filters, so it is advantageous in extracting information from 3D data compared with 2D-based CNNs or traditional diagnosis methods. MRI data from 2,124 patients were used to train and test the VRN-based 3D CNN. The network is trained to classify RCT into five classes (None, Partial, Small, Medium, Large-to-Massive). A 3D class activation map (CAM) was visualized by volume rendering to show the localization and size information of RCT in 3D. A comparative experiment was performed for the proposed method and clinical experts by using randomly selected 200 test set data, which had been separated from training set. The VRN-based 3D CNN outperformed orthopedists specialized in shoulder and general orthopedists in binary accuracy (92.5% vs. 76.4% and 68.2%), top-1 accuracy (69.0% vs. 45.8% and 30.5%), top-1±1 accuracy (87.5% vs. 79.8% and 71.0%), sensitivity (0.92 vs. 0.89 and 0.93), and specificity (0.86 vs. 0.61 and 0.26). The generated 3D CAM provided effective information regarding the 3D location and size of the tear. Given these results, the proposed method demonstrates the feasibility of artificial intelligence that can assist in clinical RCT diagnosis.
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spelling pubmed-75184472020-09-29 Automated rotator cuff tear classification using 3D convolutional neural network Shim, Eungjune Kim, Joon Yub Yoon, Jong Pil Ki, Se-Young Lho, Taewoo Kim, Youngjun Chung, Seok Won Sci Rep Article Rotator cuff tear (RCT) is one of the most common shoulder injuries. When diagnosing RCT, skilled orthopedists visually interpret magnetic resonance imaging (MRI) scan data. For automated and accurate diagnosis of RCT, we propose a full 3D convolutional neural network (CNN) based method using deep learning. This 3D CNN automatically diagnoses the presence or absence of an RCT, classifies the tear size, and provides 3D visualization of the tear location. To train the 3D CNN, the Voxception-ResNet (VRN) structure was used. This architecture uses 3D convolution filters, so it is advantageous in extracting information from 3D data compared with 2D-based CNNs or traditional diagnosis methods. MRI data from 2,124 patients were used to train and test the VRN-based 3D CNN. The network is trained to classify RCT into five classes (None, Partial, Small, Medium, Large-to-Massive). A 3D class activation map (CAM) was visualized by volume rendering to show the localization and size information of RCT in 3D. A comparative experiment was performed for the proposed method and clinical experts by using randomly selected 200 test set data, which had been separated from training set. The VRN-based 3D CNN outperformed orthopedists specialized in shoulder and general orthopedists in binary accuracy (92.5% vs. 76.4% and 68.2%), top-1 accuracy (69.0% vs. 45.8% and 30.5%), top-1±1 accuracy (87.5% vs. 79.8% and 71.0%), sensitivity (0.92 vs. 0.89 and 0.93), and specificity (0.86 vs. 0.61 and 0.26). The generated 3D CAM provided effective information regarding the 3D location and size of the tear. Given these results, the proposed method demonstrates the feasibility of artificial intelligence that can assist in clinical RCT diagnosis. Nature Publishing Group UK 2020-09-24 /pmc/articles/PMC7518447/ /pubmed/32973192 http://dx.doi.org/10.1038/s41598-020-72357-0 Text en © The Author(s) 2020, corrected publication 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Shim, Eungjune
Kim, Joon Yub
Yoon, Jong Pil
Ki, Se-Young
Lho, Taewoo
Kim, Youngjun
Chung, Seok Won
Automated rotator cuff tear classification using 3D convolutional neural network
title Automated rotator cuff tear classification using 3D convolutional neural network
title_full Automated rotator cuff tear classification using 3D convolutional neural network
title_fullStr Automated rotator cuff tear classification using 3D convolutional neural network
title_full_unstemmed Automated rotator cuff tear classification using 3D convolutional neural network
title_short Automated rotator cuff tear classification using 3D convolutional neural network
title_sort automated rotator cuff tear classification using 3d convolutional neural network
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518447/
https://www.ncbi.nlm.nih.gov/pubmed/32973192
http://dx.doi.org/10.1038/s41598-020-72357-0
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