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Cell-Type-Specific Proteogenomic Signal Diffusion for Integrating Multi-Omics Data Predicts Novel Schizophrenia Risk Genes

Accumulation of diverse types of omics data on schizophrenia (SCZ) requires a systems approach to model the interplay between genome, transcriptome, and proteome. We introduce Markov affinity-based proteogenomic signal diffusion (MAPSD), a method to model intra-cellular protein trafficking paradigms...

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Detalles Bibliográficos
Autores principales:	Doostparast Torshizi, Abolfazl, Duan, Jubao, Wang, Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518509/ https://www.ncbi.nlm.nih.gov/pubmed/32984858 http://dx.doi.org/10.1016/j.patter.2020.100091

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