Activation and degranulation of CAR-T cells using engineered antigen-presenting cell surfaces

Adoptive cell transfer of Chimeric Antigen Receptor (CAR)-T cells showed promising results in patients with B cell malignancies. However, the detailed mechanism of CAR-T cell interaction with the target tumor cells is still not well understood. This work provides a systematic method for analyzing th...

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Detalles Bibliográficos
Autores principales: Dirar, Qassim, Russell, Teal, Liu, Lumei, Ahn, Sarah, Dotti, Gianpietro, Aravamudhan, Shyam, Conforti, Laura, Yun, Yeoheung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518621/
https://www.ncbi.nlm.nih.gov/pubmed/32976541
http://dx.doi.org/10.1371/journal.pone.0238819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518621/
https://www.ncbi.nlm.nih.gov/pubmed/32976541
http://dx.doi.org/10.1371/journal.pone.0238819

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