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Determination of amyloid core regions of insulin analogues fibrils

A rapid-acting insulin lispro and long-acting insulin glargine are commonly used for the treatment of diabetes. Clinical cases have described the formation of injectable amyloidosis with these insulin analogues, but their amyloid core regions of fibrils were unknown. To reveal these regions, we have...

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Detalles Bibliográficos
Autores principales: Surin, Alexey K., Grishin, Sergei Yu., Galzitskaya, Oxana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518739/
https://www.ncbi.nlm.nih.gov/pubmed/32543316
http://dx.doi.org/10.1080/19336896.2020.1776062