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A machine learning approach to define antimalarial drug action from heterogeneous cell-based screens
Drug resistance threatens the effective prevention and treatment of an ever-increasing range of human infections. This highlights an urgent need for new and improved drugs with novel mechanisms of action to avoid cross-resistance. Current cell-based drug screens are, however, restricted to binary li...
Autores principales: | Ashdown, George W., Dimon, Michelle, Fan, Minjie, Sánchez-Román Terán, Fernando, Witmer, Kathrin, Gaboriau, David C. A., Armstrong, Zan, Ando, D. Michael, Baum, Jake |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518791/ https://www.ncbi.nlm.nih.gov/pubmed/32978158 http://dx.doi.org/10.1126/sciadv.aba9338 |
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