SOX11 promotes epithelial/mesenchymal hybrid state and alters tropism of invasive breast cancer cells

SOX11 is an embryonic mammary epithelial marker that is normally silenced prior to birth. High SOX11 levels in breast tumours are significantly associated with distant metastasis and poor outcome in breast cancer patients. Here, we show that SOX11 confers distinct features to ER-negative DCIS.com br...

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Detalles Bibliográficos
Autores principales: Oliemuller, Erik, Newman, Richard, Tsang, Siu Man, Foo, Shane, Muirhead, Gareth, Noor, Farzana, Haider, Syed, Aurrekoetxea-Rodríguez, Iskander, Vivanco, Maria dM, Howard, Beatrice A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518891/
https://www.ncbi.nlm.nih.gov/pubmed/32909943
http://dx.doi.org/10.7554/eLife.58374

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