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Natural variation in autumn expression is the major adaptive determinant distinguishing Arabidopsis FLC haplotypes

In Arabidopsis thaliana, winter is registered during vernalization through the temperature-dependent repression and epigenetic silencing of floral repressor FLOWERING LOCUS C (FLC). Natural Arabidopsis accessions show considerable variation in vernalization. However, which aspect of the FLC repressi...

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Autores principales: Hepworth, Jo, Antoniou-Kourounioti, Rea L, Berggren, Kristina, Selga, Catja, Tudor, Eleri H, Yates, Bryony, Cox, Deborah, Collier Harris, Barley Rose, Irwin, Judith A, Howard, Martin, Säll, Torbjörn, Holm, Svante, Dean, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518893/
https://www.ncbi.nlm.nih.gov/pubmed/32902380
http://dx.doi.org/10.7554/eLife.57671
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author Hepworth, Jo
Antoniou-Kourounioti, Rea L
Berggren, Kristina
Selga, Catja
Tudor, Eleri H
Yates, Bryony
Cox, Deborah
Collier Harris, Barley Rose
Irwin, Judith A
Howard, Martin
Säll, Torbjörn
Holm, Svante
Dean, Caroline
author_facet Hepworth, Jo
Antoniou-Kourounioti, Rea L
Berggren, Kristina
Selga, Catja
Tudor, Eleri H
Yates, Bryony
Cox, Deborah
Collier Harris, Barley Rose
Irwin, Judith A
Howard, Martin
Säll, Torbjörn
Holm, Svante
Dean, Caroline
author_sort Hepworth, Jo
collection PubMed
description In Arabidopsis thaliana, winter is registered during vernalization through the temperature-dependent repression and epigenetic silencing of floral repressor FLOWERING LOCUS C (FLC). Natural Arabidopsis accessions show considerable variation in vernalization. However, which aspect of the FLC repression mechanism is most important for adaptation to different environments is unclear. By analysing FLC dynamics in natural variants and mutants throughout winter in three field sites, we find that autumnal FLC expression, rather than epigenetic silencing, is the major variable conferred by the distinct Arabidopsis FLChaplotypes. This variation influences flowering responses of Arabidopsis accessions resulting in an interplay between promotion and delay of flowering in different climates to balance survival and, through a post-vernalization effect, reproductive output. These data reveal how expression variation through non-coding cis variation at FLC has enabled Arabidopsis accessions to adapt to different climatic conditions and year-on-year fluctuations.
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spelling pubmed-75188932020-09-28 Natural variation in autumn expression is the major adaptive determinant distinguishing Arabidopsis FLC haplotypes Hepworth, Jo Antoniou-Kourounioti, Rea L Berggren, Kristina Selga, Catja Tudor, Eleri H Yates, Bryony Cox, Deborah Collier Harris, Barley Rose Irwin, Judith A Howard, Martin Säll, Torbjörn Holm, Svante Dean, Caroline eLife Chromosomes and Gene Expression In Arabidopsis thaliana, winter is registered during vernalization through the temperature-dependent repression and epigenetic silencing of floral repressor FLOWERING LOCUS C (FLC). Natural Arabidopsis accessions show considerable variation in vernalization. However, which aspect of the FLC repression mechanism is most important for adaptation to different environments is unclear. By analysing FLC dynamics in natural variants and mutants throughout winter in three field sites, we find that autumnal FLC expression, rather than epigenetic silencing, is the major variable conferred by the distinct Arabidopsis FLChaplotypes. This variation influences flowering responses of Arabidopsis accessions resulting in an interplay between promotion and delay of flowering in different climates to balance survival and, through a post-vernalization effect, reproductive output. These data reveal how expression variation through non-coding cis variation at FLC has enabled Arabidopsis accessions to adapt to different climatic conditions and year-on-year fluctuations. eLife Sciences Publications, Ltd 2020-09-09 /pmc/articles/PMC7518893/ /pubmed/32902380 http://dx.doi.org/10.7554/eLife.57671 Text en © 2020, Hepworth et al http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Chromosomes and Gene Expression
Hepworth, Jo
Antoniou-Kourounioti, Rea L
Berggren, Kristina
Selga, Catja
Tudor, Eleri H
Yates, Bryony
Cox, Deborah
Collier Harris, Barley Rose
Irwin, Judith A
Howard, Martin
Säll, Torbjörn
Holm, Svante
Dean, Caroline
Natural variation in autumn expression is the major adaptive determinant distinguishing Arabidopsis FLC haplotypes
title Natural variation in autumn expression is the major adaptive determinant distinguishing Arabidopsis FLC haplotypes
title_full Natural variation in autumn expression is the major adaptive determinant distinguishing Arabidopsis FLC haplotypes
title_fullStr Natural variation in autumn expression is the major adaptive determinant distinguishing Arabidopsis FLC haplotypes
title_full_unstemmed Natural variation in autumn expression is the major adaptive determinant distinguishing Arabidopsis FLC haplotypes
title_short Natural variation in autumn expression is the major adaptive determinant distinguishing Arabidopsis FLC haplotypes
title_sort natural variation in autumn expression is the major adaptive determinant distinguishing arabidopsis flc haplotypes
topic Chromosomes and Gene Expression
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518893/
https://www.ncbi.nlm.nih.gov/pubmed/32902380
http://dx.doi.org/10.7554/eLife.57671
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