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Inhibition of PTP1B by farnesylated 2-arylbenzofurans isolated from Morus alba root bark: unraveling the mechanism of inhibition based on in vitro and in silico studies
Among the 2-arylbenzofuran derivatives isolated from Morus alba, the farnesylated 2-arylbenzofuran is a rarer constituent. The derivative has been reported to exert anti-obesity effect; however, its inhibitory effect on protein tyrosine phosphatase 1B (PTP1B) has not been investigated. In the previo...
Autores principales: | Ha, Manh Tuan, Shrestha, Srijan, Tran, Thu Huong, Kim, Jeong Ah, Woo, Mi Hee, Choi, Jae Sue, Min, Byung Sun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pharmaceutical Society of Korea
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518952/ https://www.ncbi.nlm.nih.gov/pubmed/32978714 http://dx.doi.org/10.1007/s12272-020-01269-4 |
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