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Rapidity of CNS Effect on Photoparoxysmal Response for Brivaracetam vs. Levetiracetam: A Randomized, Double-blind, Crossover Trial in Photosensitive Epilepsy Patients

INTRODUCTION: Both levetiracetam (LEV) and brivaracetam (BRV) eliminate the electroencephalogram photoparoxysmal response (PPR) in the human phase IIa photosensitivity model of epilepsy. The physiochemical properties of BRV differ from those of LEV, having higher potency and lipophilicity plus 10- t...

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Detalles Bibliográficos
Autores principales: Reed, Ronald C., Rosenfeld, William E., Lippmann, Susan M., Eijkemans, Rene M. J. C., Kasteleijn-Nolst Trenité, Dorothee G. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518996/
https://www.ncbi.nlm.nih.gov/pubmed/32949370
http://dx.doi.org/10.1007/s40263-020-00761-1