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Isolation of extracellular vesicles improves the detection of mutant DNA from plasma of metastatic melanoma patients

Detection of BRAF(V600E) within cell free tumor DNA (ctDNA) is emerging as a promising means to improve patients’ stratification or enable BRAF inhibitor (BRAFi) therapeutic monitoring in a minimally invasive manner. Here, we investigated whether extracellular vesicle-(EV)-associated-DNA (EV-DNA) ha...

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Detalles Bibliográficos
Autores principales:	Zocco, Davide, Bernardi, Simona, Novelli, Mauro, Astrua, Chiara, Fava, Paolo, Zarovni, Natasa, Carpi, Francesco M., Bianciardi, Laura, Malavenda, Ottavia, Quaglino, Pietro, Foroni, Chiara, Russo, Domenico, Chiesi, Antonio, Fierro, Maria Teresa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519075/ https://www.ncbi.nlm.nih.gov/pubmed/32978468 http://dx.doi.org/10.1038/s41598-020-72834-6

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