OTUD4 enhances TGFβ signalling through regulation of the TGFβ receptor complex

Systematic control of the transforming growth factor-β (TGFβ) pathway is essential to keep the amplitude and the intensity of downstream signalling at appropriate levels. Ubiquitination plays a crucial role in the general regulation of this pathway. Here we identify the deubiquitinating enzyme OTUD4...

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Detalles Bibliográficos
Autores principales: Jaynes, Patrick William, Iyengar, Prasanna Vasudevan, Lui, Sarah Kit Leng, Tan, Tuan Zea, Vasilevski, Natali, Wright, Sarah Christine Elizabeth, Verdile, Giuseppe, Jeyasekharan, Anand D., Eichhorn, Pieter Johan Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519109/
https://www.ncbi.nlm.nih.gov/pubmed/32973272
http://dx.doi.org/10.1038/s41598-020-72791-0

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