Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity

Poly(ADP-ribosyl)ation is a reversible post-translational modification synthetized by ADP-ribose transferases and removed by poly(ADP-ribose) glycohydrolase (PARG), which plays important roles in DNA damage repair. While well-studied in somatic tissues, much less is known about poly(ADP-ribosyl)atio...

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Detalles Bibliográficos
Autores principales: Janisiw, Eva, Raices, Marilina, Balmir, Fabiola, Paulin, Luis F., Baudrimont, Antoine, von Haeseler, Arndt, Yanowitz, Judith L., Jantsch, Verena, Silva, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519143/
https://www.ncbi.nlm.nih.gov/pubmed/32978394
http://dx.doi.org/10.1038/s41467-020-18693-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519143/
https://www.ncbi.nlm.nih.gov/pubmed/32978394
http://dx.doi.org/10.1038/s41467-020-18693-1

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