PTPN14 aggravates inflammation through promoting proteasomal degradation of SOCS7 in acute liver failure

Acute liver failure (ALF) is a rare but life-threatening systemic disorder. The innate immune regulation has an important role in this process; however, the specific mechanisms are not completely clear. Using the LPS + D-GalN-induced ALF mouse model, we found that the survival rate of PTPN14-deficie...

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Detalles Bibliográficos
Autores principales: Fu, Beibei, Yin, Songna, Lin, Xiaoyuan, Shi, Lei, Wang, Yu, Zhang, Shanfu, Zhao, Qingting, Li, Zhifeng, Yang, Yanling, Wu, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519157/
https://www.ncbi.nlm.nih.gov/pubmed/32978373
http://dx.doi.org/10.1038/s41419-020-03014-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519157/
https://www.ncbi.nlm.nih.gov/pubmed/32978373
http://dx.doi.org/10.1038/s41419-020-03014-7

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