Cargando…
Zi Shen Huo Luo Formula Prevents Aldosterone-Induced Cardiomyocyte Hypertrophy and Cardiac Fibroblast Proliferation by Regulating the Striatin-Mediated MR/EGFR/ERK Signaling Pathway
Inappropriate activation of the renin-angiotensin-aldosterone system (RAAS) is an important factor in the development of hypertension. Excessive aldosterone can lead to myocardial extracellular matrix collagen proliferation, fibrosis, and cardiomyocyte hypertrophy and aggravate maladaptive remodelin...
Autores principales: | Feng, Weike, Zhao, Yue, Song, Xiaotong, Wang, Yuan, Chen, Qian, Zhao, Haijun, Lu, Guangying, Yuan, Hongyan, Wu, Zhichun, Yu, Huayun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519188/ https://www.ncbi.nlm.nih.gov/pubmed/33014117 http://dx.doi.org/10.1155/2020/9028047 |
Ejemplares similares
-
Zi Shen Huo Luo Formula Enhances the Therapeutic Effects of Angiotensin-Converting Enzyme Inhibitors on Hypertensive Left Ventricular Hypertrophy by Interfering With Aldosterone Breakthrough and Affecting Caveolin-1/Mineralocorticoid Receptor Colocalization and Downstream Extracellular Signal-Regulated Kinase Signaling
por: Song, Xiaotong, et al.
Publicado: (2020) -
Mechanisms and Molecular Targets of BuShenHuoXue Formula
for Osteoarthritis
por: Xiong, Wen, et al.
Publicado: (2022) -
Enhanced Thrombotic Responses Are Associated With Striatin Deficiency and Aldosterone
por: Gromotowicz‐Poplawska, Anna, et al.
Publicado: (2021) -
Striatin heterozygous mice are more sensitive to aldosterone-induced injury
por: Garza, Amanda E, et al.
Publicado: (2020) -
Microarray Analysis Reveals the Molecular Basis of Antiarthritic Activity of Huo-Luo-Xiao-Ling Dan
por: Yu, Hua, et al.
Publicado: (2013)