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A case report of anorectal malignant melanoma in the transitional zone
INTRODUCTION: Anorectal malignant melanoma is an uncommon and highly malignant disease with a greater incidence in females. Many patients were misdiagnosed as hemorrhoids, benign polyps, and rectal cancer. They were often diagnosed in an advanced stage. Wide local excision and abdominoperineal resec...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519280/ https://www.ncbi.nlm.nih.gov/pubmed/32979823 http://dx.doi.org/10.1016/j.ijscr.2020.09.091 |
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author | Nguyen, Minh Thao Nguyen, Van Mao Tran, Van Huy Pham, Anh Vu |
author_facet | Nguyen, Minh Thao Nguyen, Van Mao Tran, Van Huy Pham, Anh Vu |
author_sort | Nguyen, Minh Thao |
collection | PubMed |
description | INTRODUCTION: Anorectal malignant melanoma is an uncommon and highly malignant disease with a greater incidence in females. Many patients were misdiagnosed as hemorrhoids, benign polyps, and rectal cancer. They were often diagnosed in an advanced stage. Wide local excision and abdominoperineal resection are the main treatments of rectal melanoma. PRESENTATION OF CASE: A case report is a 77-year-old man who has blood in the stool for 4 months without clinical examination. He admitted to the emergency room with sudden syndromes that related to bowel perforation. Rectal examination detected a large anorectal polyp. Computer tomography showed free air and fluid in the peritoneal cavity. He was received laparoscopic surgery and found the fishbone penetrated the sigmoid colon without polyp resection. The polyp was treated by local excision a few days later. The histology examination was a primary malignant melanoma. Due to the pigmented lesion that remained from the resected polyp’s root, the abdominoperineal resection was performed as a radical treatment. DISCUSSION: Diagnosis of anorectal malignant melanoma is difficult because of atypical signs, that are confused with bleeding hemorrhoids especially an amelanotic melanoma. Treatment is controversial, including surgery, radiotherapy, chemotherapy, and target therapy. A present case is an option in radical surgery. CONCLUSION: Anorectal melanoma is a rare disease with poor results and prognosis. A lack of large-data leads to a missing evidence-based guideline in this disease. Early-staging diagnosis and surgical treatment help patients improve their overall survival. |
format | Online Article Text |
id | pubmed-7519280 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-75192802020-09-30 A case report of anorectal malignant melanoma in the transitional zone Nguyen, Minh Thao Nguyen, Van Mao Tran, Van Huy Pham, Anh Vu Int J Surg Case Rep Case Report INTRODUCTION: Anorectal malignant melanoma is an uncommon and highly malignant disease with a greater incidence in females. Many patients were misdiagnosed as hemorrhoids, benign polyps, and rectal cancer. They were often diagnosed in an advanced stage. Wide local excision and abdominoperineal resection are the main treatments of rectal melanoma. PRESENTATION OF CASE: A case report is a 77-year-old man who has blood in the stool for 4 months without clinical examination. He admitted to the emergency room with sudden syndromes that related to bowel perforation. Rectal examination detected a large anorectal polyp. Computer tomography showed free air and fluid in the peritoneal cavity. He was received laparoscopic surgery and found the fishbone penetrated the sigmoid colon without polyp resection. The polyp was treated by local excision a few days later. The histology examination was a primary malignant melanoma. Due to the pigmented lesion that remained from the resected polyp’s root, the abdominoperineal resection was performed as a radical treatment. DISCUSSION: Diagnosis of anorectal malignant melanoma is difficult because of atypical signs, that are confused with bleeding hemorrhoids especially an amelanotic melanoma. Treatment is controversial, including surgery, radiotherapy, chemotherapy, and target therapy. A present case is an option in radical surgery. CONCLUSION: Anorectal melanoma is a rare disease with poor results and prognosis. A lack of large-data leads to a missing evidence-based guideline in this disease. Early-staging diagnosis and surgical treatment help patients improve their overall survival. Elsevier 2020-09-17 /pmc/articles/PMC7519280/ /pubmed/32979823 http://dx.doi.org/10.1016/j.ijscr.2020.09.091 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Nguyen, Minh Thao Nguyen, Van Mao Tran, Van Huy Pham, Anh Vu A case report of anorectal malignant melanoma in the transitional zone |
title | A case report of anorectal malignant melanoma in the transitional zone |
title_full | A case report of anorectal malignant melanoma in the transitional zone |
title_fullStr | A case report of anorectal malignant melanoma in the transitional zone |
title_full_unstemmed | A case report of anorectal malignant melanoma in the transitional zone |
title_short | A case report of anorectal malignant melanoma in the transitional zone |
title_sort | case report of anorectal malignant melanoma in the transitional zone |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519280/ https://www.ncbi.nlm.nih.gov/pubmed/32979823 http://dx.doi.org/10.1016/j.ijscr.2020.09.091 |
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